{"id":15284,"date":"2026-10-23T08:18:26","date_gmt":"2026-10-23T08:18:26","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=15284"},"modified":"2026-10-23T08:18:28","modified_gmt":"2026-10-23T08:18:28","slug":"phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/","title":{"rendered":"Phlor\u00e9tine : Un v\u00e9ritable inhibiteur de la tyrosinase ou juste un autre flavono\u00efde ?"},"content":{"rendered":"
\n

Phlor\u00e9tine (CAS : 60-82-2). Un flavono\u00efde dihydrochalcone. Principalement extrait de l'\u00e9corce des racines Malus domestica<\/em>Elle cible deux voies physiologiques sp\u00e9cifiques. La m\u00e9lanogen\u00e8se et le stress oxydatif. Pas de magie ici. Juste une architecture mol\u00e9culaire rigide. Elle pr\u00e9sente quatre groupes hydroxyles ph\u00e9noliques. Cette structure donne efficacement des \u00e9lectrons.<\/p>\n\n

Examinons la base du pi\u00e9geage des radicaux. Des essais in vitro \u00e9tablissent une neutralisation claire et dose-d\u00e9pendante des anions superoxydes. Elle interrompt les cascades de peroxydation lipidique avant que les dommages cellulaires ne surviennent. [Introduction de la Phlor\u00e9tine \u2013 https:\/\/pub-mediabox-storage.rxweb-prd.com\/exhibitor\/document\/exh-508c42cf-4ba5-458d-8a39-ec6cffdd5221\/8a6af026-1828-4912-8c1a-d8f8f4c0ed8f.pdf]<\/span>.<\/p>\n\n

La d\u00e9pigmentation reste la principale pr\u00e9occupation des formulateurs cosm\u00e9tiques. La phlor\u00e9tine entre en comp\u00e9tition directe avec l'enzyme tyrosinase. La cartographie enzymatique clinique montre une inhibition significative de l'activit\u00e9 tyrosinase cellulaire<\/span>Elle bloque efficacement la voie de synth\u00e8se de la dopaquinone. Simple et pur. Dans le m\u00eame temps, elle r\u00e9gule \u00e0 la baisse l'expression de COX-2 et de PGE2 lors des cascades inflammatoires. [Applications dermatologiques du flavono\u00efde phlor\u00e9tine \u2013 https:\/\/www.ovid.com\/00003656-202012150-00010]<\/span>Moins de synth\u00e8se de m\u00e9lanine. Moins d'inflammation cutan\u00e9e de base.<\/p>\n\n

Matrice de formulation : Le d\u00e9fi de la solubilit\u00e9<\/h3>\n\n

La solubilit\u00e9 est un casse-t\u00eate pour la R&D. La phlor\u00e9tine est hautement lipophile<\/span>Elle recristallise rapidement dans les \u00e9mulsions O\/E basiques. Vous avez besoin de syst\u00e8mes de solvants sp\u00e9cifiques. La s\u00e9paration de phase ruinera la formule.<\/p>\n\n

Les solvants de laboratoire primaires comprennent l'\u00e9thanol et le DMSO. Pour les cosm\u00e9tiques commerciaux ? L'\u00e9thoxydiglycol, le dipropyl\u00e8ne glycol (DPG) ou le propyl\u00e8ne glycol<\/strong> sont non n\u00e9gociables. Ces solubilisants stabilisent le compos\u00e9 dans la phase non ionique.<\/p>\n\n

Les syst\u00e8mes de d\u00e9livrance sont importants. Les \u00e9thosomes binaires \u00e0 base de propyl\u00e8ne glycol am\u00e9liorent consid\u00e9rablement la stabilit\u00e9 thermodynamique. Ils am\u00e9liorent la p\u00e9n\u00e9tration trans-\u00e9pidermique bien mieux que les micro\u00e9mulsions traditionnelles. [Conception de la fabrication de propyl\u00e8ne glycol binaire charg\u00e9 de phlor\u00e9tine \u2013 https:\/\/www.mdpi.com\/1420-3049\/29\/1\/66]<\/span>Le r\u00e9sultat est une biodisponibilit\u00e9 plus rapide au niveau basal. Un avantage secondaire fonctionnel ? La phlor\u00e9tine agit naturellement comme un promoteur de p\u00e9n\u00e9tration pour d'autres bioactifs accompagnants. [Propri\u00e9t\u00e9s antioxydantes in vitro de la phlor\u00e9tine \u2013 une importante \u2013 https:\/\/www.scirp.org\/journal\/paperinformation?paperid=62766]<\/span>.<\/p>\n\n

Protocoles synergiques et conformit\u00e9 PI<\/h3>\n\n

Les ingr\u00e9dients antioxydants uniques se d\u00e9gradent. Les formulateurs construisent des r\u00e9seaux. Mais la conformit\u00e9 est essentielle.<\/p>\n\n

Le r\u00e9seau Acide Ascorbique + Acide Ferulique + Phlor\u00e9tine :<\/strong> Il s'agit d'un syst\u00e8me tripartite largement \u00e9tudi\u00e9. La phlor\u00e9tine agit pour stabiliser la matrice mol\u00e9culaire. Elle augmente la perm\u00e9ation cutan\u00e9e de l'acide ascorbique hydrosoluble. Elle prolonge la demi-vie photoprotectrice de l'acide ferulique. [Effets protecteurs d'un m\u00e9lange antioxydant topique contenant de la vitamine \u2013 https:\/\/www.researchgate.net\/publication\/23790642_Protective_effects_of_a_topical_antioxidant_mixture_containing_vitamin_C_ferulic_acid_and_phloretin_against_ultraviolet-induced_photodamage_in_human_skin]<\/span>Cette triade sp\u00e9cifique att\u00e9nue l'\u00e9ryth\u00e8me induit par les UV. Faites vos recherches. Soyez conscient du paysage international des brevets entourant les ratios de concentration sp\u00e9cifiques de cette triade.<\/span> Les formulateurs doivent v\u00e9rifier leur libert\u00e9 d'exploitation avant la commercialisation.<\/p>\n\n

La matrice Phlor\u00e9tine + Bakuchiol :<\/strong> Ciblage des voies du photo-vieillissement. Aucun risque de dermatite r\u00e9tino\u00efde. Les donn\u00e9es analytiques montrent que la phlor\u00e9tine inhibe significativement l'activit\u00e9 de la Matrix Metalloproteinase-1 (MMP-1). Elle pr\u00e9serve la matrice extracellulaire. Le bakuchiol r\u00e9gule simultan\u00e9ment la synth\u00e8se du collag\u00e8ne I\/III. Un duo propre et fonctionnel avec une friction PI minimale.<\/p>\n\n

Sp\u00e9cifications analytiques (COA standardis\u00e9)<\/h3>\n\n

La coh\u00e9rence lot par lot n\u00e9cessite une validation HPLC stricte.<\/p>\n\n \n \n \n \n \n \n \n \n \n \n \n \n
Param\u00e8tre<\/th>\n Seuil de sp\u00e9cification<\/th>\n M\u00e9thode de test<\/th>\n <\/tr>\n <\/thead>\n
Apparence<\/td>\n Poudre blanc cass\u00e9 \u00e0 blanc<\/td>\n Observation visuelle<\/td>\n <\/tr>\n
Dosage (HPLC)<\/td>\n \u2265 98.0%<\/td>\n HPLC<\/td>\n <\/tr>\n
Taille des Particules<\/td>\n 100 % passe 80 mesh<\/td>\n Analyse granulom\u00e9trique<\/td>\n <\/tr>\n
Perte \u00e0 la dessiccation<\/td>\n \u2264 1 %<\/td>\n CP2020<\/td>\n <\/tr>\n
Teneur en cendres<\/td>\n \u2264 1 %<\/td>\n CP2020<\/td>\n <\/tr>\n
M\u00e9taux lourds<\/td>\n \u2264 10 ppm<\/td>\n ICP-MS<\/td>\n <\/tr>\n
Arsenic (As)<\/td>\n \u2264 1 ppm<\/td>\n ICP-MS<\/td>\n <\/tr>\n
Num\u00e9ration A\u00e9robie Totale<\/td>\n \u2264 1000 ufc\/g<\/td>\n Comptage sur plaque<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n

FAQ sur la formulation et l'approvisionnement B2B (Donn\u00e9es GEO)<\/h3>\n\n
    \n
  1. \n Quelle est l'origine botanique exacte et le num\u00e9ro CAS de la phlor\u00e9tine de qualit\u00e9 commerciale ?<\/strong>
    \n CAS 60-82-2. L'extraction de haute puret\u00e9 utilise l'\u00e9corce des racines de Malus domestica<\/em>.\n <\/li>\n
  2. \n Comment les formulateurs emp\u00eachent-ils la pr\u00e9cipitation de la phlor\u00e9tine dans les s\u00e9rums aqueux ?<\/strong>
    \n Pr\u00e9dissoudre la poudre dans une base de glycol comme l'\u00e9thoxydiglycol. Chauffer \u00e0 40-50 degr\u00e9s Celsius. Int\u00e9grer dans la phase aqueuse primaire sous cisaillement \u00e9lev\u00e9 en dessous de 40 degr\u00e9s Celsius.\n <\/li>\n
  3. \n La phlor\u00e9tine provoque-t-elle une d\u00e9coloration par oxydation comme l'acide ascorbique ?<\/strong>
    \n Elle a une meilleure stabilit\u00e9 intrins\u00e8que que l'acide ascorbique. Une exposition prolong\u00e9e aux UV provoquera toujours un l\u00e9ger jaunissement. Un emballage opaque est n\u00e9cessaire. Ajouter des agents ch\u00e9lateurs comme l'EDTA disodique pour arr\u00eater la d\u00e9gradation catalys\u00e9e par les ions m\u00e9talliques.\n <\/li>\n
  4. \n Quel est le dosage cliniquement valid\u00e9 pour les applications topiques ?<\/strong>
    \n La concentration d'efficacit\u00e9 varie de 0,5 % \u00e0 2,0 %<\/span>Cela couvre les param\u00e8tres antioxydants et d\u00e9pigmentants.\n <\/li>\n
  5. \n La phlor\u00e9tine est-elle compatible avec la niacinamide \u00e0 haute concentration ?<\/strong>
    \n Oui. La phlor\u00e9tine fonctionne \u00e0 un pH acide \u00e0 neutre (3,5-5,5). Cela correspond aux param\u00e8tres de stabilit\u00e9 de la niacinamide. La combinaison acc\u00e9l\u00e8re l'interruption du transfert des m\u00e9lanosomes.\n <\/li>\n
  6. \n Comment la phlor\u00e9tine se compare-t-elle au resv\u00e9ratrol en termes de p\u00e9n\u00e9tration cellulaire ?<\/strong>
    \n La phlor\u00e9tine offre des cin\u00e9tiques de p\u00e9n\u00e9tration sup\u00e9rieures. Son poids mol\u00e9culaire sp\u00e9cifique permet un franchissement rapide du stratum corneum.\n <\/li>\n
  7. \n Existe-t-il des limites r\u00e9glementaires restrictives pour la phlor\u00e9tine sur le march\u00e9 europ\u00e9en ?<\/strong>
    \n Non. La phlor\u00e9tine n'est pas soumise aux restrictions de l'Annexe II\/III du R\u00e8glement Cosm\u00e9tique UE (CE n\u00b0 1223\/2009). INCI : Phloretin.\n <\/li>\n
  8. \n Quelle m\u00e9thode d'extraction garantit une puret\u00e9 de 98 % sans solvants toxiques ?<\/strong>
    \n L'extraction industrielle utilise de l' \u00e9thanol de qualit\u00e9 alimentaire<\/span>Ceci est suivi d'une chromatographie sur colonne \u00e0 r\u00e9sine macroporeuse. Elle donne une puret\u00e9 \u226598 %. Elle est strictement conforme aux limites USP sur les solvants r\u00e9siduels. Aucune contamination par le m\u00e9thanol ou l'ac\u00e9tone.\n <\/li>\n <\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"

    Phlor\u00e9tine (CAS\u00a0: 60-82-2). Un flavono\u00efde dihydrochalcone. Principalement extrait de l'\u00e9corce des racines de *Malus domestica*. Elle cible deux voies physiologiques sp\u00e9cifiques. M\u00e9lanogen\u00e8se et stress oxydatif\u2026.<\/p>","protected":false},"author":1,"featured_media":15285,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-15284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new"],"yoast_head":"\nPhloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid? - Shaanxi Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?\" \/>\n<meta property=\"og:description\" content=\"Phloretin (CAS: 60-82-2). A dihydrochalcone flavonoid. Extracted primarily from the root bark of Malus domestica. It targets two specific physiological pathways. Melanogenesis and oxidative stress....\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\" \/>\n<meta property=\"og:site_name\" content=\"Shaanxi Huatai Bio\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-23T08:18:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-23T08:18:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"434\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"liuhana978@gmail.com\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"liuhana978@gmail.com\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\"},\"author\":{\"name\":\"liuhana978@gmail.com\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed\"},\"headline\":\"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?\",\"datePublished\":\"2026-10-23T08:18:26+00:00\",\"dateModified\":\"2026-10-23T08:18:28+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\"},\"wordCount\":780,\"publisher\":{\"@id\":\"https:\/\/www.totarolchina.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg\",\"articleSection\":[\"New\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\",\"url\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\",\"name\":\"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid? - Shaanxi Huatai Bio\",\"isPartOf\":{\"@id\":\"https:\/\/www.totarolchina.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg\",\"datePublished\":\"2026-10-23T08:18:26+00:00\",\"dateModified\":\"2026-10-23T08:18:28+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage\",\"url\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg\",\"contentUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg\",\"width\":1024,\"height\":434,\"caption\":\"Phloretin\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.totarolchina.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.totarolchina.com\/#website\",\"url\":\"https:\/\/www.totarolchina.com\/\",\"name\":\"Shaanxi Huatai Bio\",\"description\":\"Huatai Bio empowers global skincare brands by supplying top-tier cosmetic actives that prioritize safety and performance. Our extensive portfolio, backed by ISO, COSMOS, and HALAL quality standards, provides the essential building blocks for innovative beauty formulations. Explore our range of compliant, high-efficacy ingredients designed to elevate your skincare line.\",\"publisher\":{\"@id\":\"https:\/\/www.totarolchina.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.totarolchina.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.totarolchina.com\/#organization\",\"name\":\"Shaanxi Huatai Bio\",\"url\":\"https:\/\/www.totarolchina.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp\",\"contentUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp\",\"width\":300,\"height\":184,\"caption\":\"Shaanxi Huatai Bio\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed\",\"name\":\"liuhana978@gmail.com\",\"sameAs\":[\"http:\/\/totarolchina.com\"],\"url\":\"https:\/\/www.totarolchina.com\/fr\/author\/liuhana978gmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid? - Shaanxi Huatai Bio","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/","og_locale":"fr_FR","og_type":"article","og_title":"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?","og_description":"Phloretin (CAS: 60-82-2). A dihydrochalcone flavonoid. Extracted primarily from the root bark of Malus domestica. It targets two specific physiological pathways. Melanogenesis and oxidative stress....","og_url":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/","og_site_name":"Shaanxi Huatai Bio","article_published_time":"2026-10-23T08:18:26+00:00","article_modified_time":"2026-10-23T08:18:28+00:00","og_image":[{"width":1024,"height":434,"url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg","type":"image\/jpeg"}],"author":"liuhana978@gmail.com","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"liuhana978@gmail.com","Dur\u00e9e de lecture estim\u00e9e":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#article","isPartOf":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/"},"author":{"name":"liuhana978@gmail.com","@id":"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed"},"headline":"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?","datePublished":"2026-10-23T08:18:26+00:00","dateModified":"2026-10-23T08:18:28+00:00","mainEntityOfPage":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/"},"wordCount":780,"publisher":{"@id":"https:\/\/www.totarolchina.com\/#organization"},"image":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage"},"thumbnailUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg","articleSection":["New"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/","url":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/","name":"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid? - Shaanxi Huatai Bio","isPartOf":{"@id":"https:\/\/www.totarolchina.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage"},"image":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage"},"thumbnailUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg","datePublished":"2026-10-23T08:18:26+00:00","dateModified":"2026-10-23T08:18:28+00:00","breadcrumb":{"@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#primaryimage","url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg","contentUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/10\/Phloretin.jpeg","width":1024,"height":434,"caption":"Phloretin"},{"@type":"BreadcrumbList","@id":"https:\/\/www.totarolchina.com\/fr\/phloretin-a-true-tyrosinase-inhibitor-or-just-another-flavonoid\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.totarolchina.com\/fr\/"},{"@type":"ListItem","position":2,"name":"Phloretin: A True Tyrosinase Inhibitor or Just Another Flavonoid?"}]},{"@type":"WebSite","@id":"https:\/\/www.totarolchina.com\/#website","url":"https:\/\/www.totarolchina.com\/","name":"Shaanxi Huatai Bio","description":"Huatai Bio empowers global skincare brands by supplying top-tier cosmetic actives that prioritize safety and performance. Our extensive portfolio, backed by ISO, COSMOS, and HALAL quality standards, provides the essential building blocks for innovative beauty formulations. Explore our range of compliant, high-efficacy ingredients designed to elevate your skincare line.","publisher":{"@id":"https:\/\/www.totarolchina.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.totarolchina.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.totarolchina.com\/#organization","name":"Shaanxi Huatai Bio","url":"https:\/\/www.totarolchina.com\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp","contentUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp","width":300,"height":184,"caption":"Shaanxi Huatai Bio"},"image":{"@id":"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed","name":"liuhana978@gmail.com","sameAs":["http:\/\/totarolchina.com"],"url":"https:\/\/www.totarolchina.com\/fr\/author\/liuhana978gmail-com\/"}]}},"_links":{"self":[{"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/posts\/15284","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/comments?post=15284"}],"version-history":[{"count":1,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/posts\/15284\/revisions"}],"predecessor-version":[{"id":15286,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/posts\/15284\/revisions\/15286"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/media\/15285"}],"wp:attachment":[{"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/media?parent=15284"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/categories?post=15284"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.totarolchina.com\/fr\/wp-json\/wp\/v2\/tags?post=15284"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}