{"id":15419,"date":"2026-11-12T07:42:29","date_gmt":"2026-11-12T07:42:29","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=15419"},"modified":"2026-11-12T07:42:31","modified_gmt":"2026-11-12T07:42:31","slug":"soothing-skincare-claims-what-dipotassium-glycyrrhizate-research-can-support","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/fr\/soothing-skincare-claims-what-dipotassium-glycyrrhizate-research-can-support\/","title":{"rendered":"All\u00e9gations de soins de la peau apaisants : Ce que la recherche sur le dipotassium glycyrrhizate peut soutenir"},"content":{"rendered":"
\n

\n Un pan\u00e9liste d\u00e9clare qu'un s\u00e9rum pique moins que la version pr\u00e9c\u00e9dente. L'\u00e9valuateur constate peu de changement dans la rougeur du visage. Les deux observations peuvent \u00eatre valides. Le Forum International pour l'\u00c9tude du Prurit d\u00e9crit la peau sensible en termes de sensations d\u00e9sagr\u00e9ables, notamment des picotements et des br\u00fblures<\/span>, et note que la peau peut para\u00eetre normale ou pr\u00e9senter un \u00e9ryth\u00e8me (Misery et al., 2017). Pour une \u00e9quipe de d\u00e9veloppement cosm\u00e9tique, cela soul\u00e8ve une question concr\u00e8te : Quel changement compterait comme un succ\u00e8s pour ce produit ?<\/strong>\n <\/p>\n\n

Ce que le d\u00e9fi de l'acide lactique a r\u00e9ellement r\u00e9v\u00e9l\u00e9<\/h2>\n\n

\n Le diglycyrrhizate de dipotassium offre un exemple utile de l'importance de l'endpoint. Yashiki et al. ont compar\u00e9 deux cr\u00e8mes contenant 5% d'acide lactique, l'une avec 0,2% de diglycyrrhizate de dipotassium et l'autre sans. Les chercheurs ont enregistr\u00e9 plusieurs types d'inconfort. Dans la section des r\u00e9sultats, ils ont rapport\u00e9 une tendance \u00e0 des scores d'inconfort li\u00e9s aux d\u00e9mangeaisons plus faibles<\/span> chez les six participants analys\u00e9s. L'article qualifie la proc\u00e9dure de test de picotement, mais le r\u00e9sultat d\u00e9crit dans cette section concerne les d\u00e9mangeaisons. Cette distinction est importante si la revendication examin\u00e9e porte sp\u00e9cifiquement sur les picotements ou les br\u00fblures.<\/em>\n <\/p>\n\n

\n Le m\u00eame article a examin\u00e9 l'expression du g\u00e8ne du facteur de croissance nerveuse dans des k\u00e9ratinocytes cultiv\u00e9s. Le diglycyrrhizate de dipotassium a supprim\u00e9 l'augmentation induite par la substance P dans les conditions de test. Les auteurs n'ont pas pr\u00e9cis\u00e9 ce qui expliquait la tendance sensorielle dans le test humain. Pour la R&D, le r\u00e9sultat cellulaire fournit une raison d'\u00e9tudier le confort cutan\u00e9, et la petite \u00e9tude humaine aide \u00e0 identifier une sensation digne d'un suivi.\n <\/p>\n\n

Int\u00e9grer le b\u00e9n\u00e9fice vis\u00e9 dans le brief<\/h2>\n\n
\n \n \n \n \n \n \n \n
Si le produit est destin\u00e9 \u00e0\u2026<\/th>\n \u00c9valuer ceci dans le produit fini<\/th>\n <\/tr>\n <\/thead>\n
\u00catre plus confortable \u00e0 l'application<\/td>\n Demander aux participants de noter la sensation nomm\u00e9e dans le brief, telle que les picotements ou les br\u00fblures, \u00e0 des moments pr\u00e9cis apr\u00e8s l'application.<\/td>\n <\/tr>\n
Rendre la rougeur visible moins perceptible<\/td>\n \u00c9valuer la rougeur sur des sites constants dans des conditions standardis\u00e9es \u00e0 l'aide d'une note visuelle, d'une imagerie calibr\u00e9e ou d'un instrument appropri\u00e9.<\/td>\n <\/tr>\n
Soutenir la r\u00e9cup\u00e9ration de la barri\u00e8re<\/td>\n Suivre la perte d'eau trans\u00e9pidermique (TEWL) sur une p\u00e9riode de r\u00e9cup\u00e9ration d\u00e9finie. Enregistrer l'hydratation s\u00e9par\u00e9ment si le brief inclut \u00e9galement un b\u00e9n\u00e9fice hydratant.<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n <\/div>\n\n

\n La distinction peut modifier une d\u00e9cision de formulation. Si les pan\u00e9listes signalent qu'un prototype pique imm\u00e9diatement, notez quand cela commence et combien de temps cela dure. Examinez la base avant de d\u00e9cider qu'elle n\u00e9cessite un actif apaisant suppl\u00e9mentaire. Si la base r\u00e9pond d\u00e9j\u00e0 aux crit\u00e8res de tol\u00e9rance de l'\u00e9quipe et que la question est de savoir si le diglycyrrhizate de dipotassium ajoute un b\u00e9n\u00e9fice de confort, comparez des versions appari\u00e9es avec et sans l'ingr\u00e9dient.<\/span> Gardez les autres actifs et les conditions d'application identiques, et v\u00e9rifiez le pH final des deux versions.\n <\/p>\n\n

\n Cela modifie \u00e9galement ce qu'il faut rechercher dans le dossier de preuves d'un fournisseur. Lorsqu'une diapositive indique \"apaisant\", regardez l'endpoint sur le graphique. Un marqueur cellulaire, un score de d\u00e9mangeaisons et une note de rougeur faciale r\u00e9pondent \u00e0 des questions diff\u00e9rentes. Pour un brief centr\u00e9 sur le confort d'application, les donn\u00e9es du d\u00e9fi humain sont un point de d\u00e9part. Pour un brief centr\u00e9 sur la rougeur visible, demandez une \u00e9tude qui a mesur\u00e9 la rougeur dans une formule finie pertinente.<\/span>\n <\/p>\n\n

FAQ<\/h2>\n\n
\n

Un produit peut-il \u00eatre plus apaisant sans modifier la rougeur visible ?<\/strong><\/p>\n

Oui. Le confort cutan\u00e9 et la rougeur visible peuvent \u00eatre \u00e9valu\u00e9s s\u00e9par\u00e9ment. Choisissez l'endpoint qui correspond \u00e0 la revendication vis\u00e9e.<\/p>\n\n

Qu'a trouv\u00e9 l'\u00e9tude humaine sur le diglycyrrhizate de dipotassium ?<\/strong><\/p>\n

Chez les six participants analys\u00e9s, les auteurs ont rapport\u00e9 une tendance \u00e0 des scores d'inconfort li\u00e9s aux d\u00e9mangeaisons plus faibles avec la cr\u00e8me contenant du diglycyrrhizate de dipotassium dans le cadre d'un d\u00e9fi \u00e0 l'acide lactique.<\/p>\n\n

0,2% est-il un niveau d'utilisation recommand\u00e9 ?<\/strong><\/p>\n

C'\u00e9tait le niveau test\u00e9 dans cette \u00e9tude. Utilisez-le comme r\u00e9f\u00e9rence d'\u00e9tude lors de l'\u00e9valuation d'un niveau pour votre propre formule.<\/p>\n\n

Une \u00e9tude sur les k\u00e9ratinocytes peut-elle \u00e9tayer une revendication d'apaisement du produit fini ?<\/strong><\/p>\n

Elle peut fournir une justification pour la s\u00e9lection d'un actif. \u00c9valuez le b\u00e9n\u00e9fice vis\u00e9 dans le produit fini pour \u00e9tayer la revendication.<\/p>\n\n

Que dois-je demander lors de l'examen des donn\u00e9es apaisantes d'un fournisseur ?<\/strong><\/p>\n

Demandez quel mat\u00e9riel et quelle formule ont \u00e9t\u00e9 test\u00e9s, ce que contenait le contr\u00f4le et quel endpoint l'\u00e9tude a mesur\u00e9.<\/p>\n <\/div>\n\n

R\u00e9f\u00e9rences<\/h2>\n
    \n
  • Misery, L., et al. (2017). D\u00e9finition de la peau sensible\u00a0: un document de position d\u2019experts du groupe d\u2019int\u00e9r\u00eat sp\u00e9cial sur la peau sensible du Forum international pour l\u2019\u00e9tude du prurit. Acta Dermato-Venereologica, 97(1), 4\u20136.<\/li>\n
  • Yashiki, K., Ohto, N., Kawashima, Y., & Nakahara, T. (2017, listing J-STAGE). The Effect of Dipotassium Glycyrrhiza on Sensitive Skin Care. Journal of Society of Cosmetic Chemists of Japan, 50(4), 334\u2013339.<\/li>\n <\/ul>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

    Un pan\u00e9liste d\u00e9clare qu'un s\u00e9rum pique moins que la version pr\u00e9c\u00e9dente. L'\u00e9valuateur constate peu de changement dans la rougeur du visage. Les deux observations peuvent \u00eatre valides. Le\u2026<\/p>","protected":false},"author":1,"featured_media":15420,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-15419","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new"],"yoast_head":"\nSoothing Skincare Claims: What Dipotassium Glycyrrhizate Research Can Support - Shaanxi Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.totarolchina.com\/fr\/soothing-skincare-claims-what-dipotassium-glycyrrhizate-research-can-support\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Soothing Skincare Claims: What Dipotassium Glycyrrhizate Research Can Support\" \/>\n<meta property=\"og:description\" content=\"A panelist says a serum stings less than the previous version. 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