{"id":14480,"date":"2026-05-15T06:10:12","date_gmt":"2026-05-15T06:10:12","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=14480"},"modified":"2026-06-03T07:58:50","modified_gmt":"2026-06-03T07:58:50","slug":"hydroxypropyl-tetrahydropyrantriol-in-skin-care-ecm-innovation","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/ja\/hydroxypropyl-tetrahydropyrantriol-in-skin-care-ecm-innovation\/","title":{"rendered":"\u30b9\u30ad\u30f3\u30b1\u30a2\u306b\u304a\u3051\u308b\u30d2\u30c9\u30ed\u30ad\u30b7\u30d7\u30ed\u30d4\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30d4\u30e9\u30f3\u30c8\u30ea\u30aa\u30fc\u30eb\uff1aECM\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3"},"content":{"rendered":"

\u5148\u9031\u6728\u66dc\u65e5\u306e\u771f\u591c\u4e2d\u306b\u3001\u3042\u308b\u30e1\u30c7\u30a3\u30ab\u30eb\u30b9\u30d1\u30d6\u30e9\u30f3\u30c9\u306e\u30aa\u30fc\u30ca\u30fc\u304b\u3089\u30e1\u30c3\u30bb\u30fc\u30b8\u304c\u5c4a\u304d\u307e\u3057\u305f\u3002\u5f7c\u306e\u30e9\u30dc\u3067\u306f\u3001\u5f37\u529b\u306a\u30da\u30d7\u30c1\u30c9\u30d6\u30ec\u30f3\u30c9\u3092\u4f7f\u7528\u3057\u305f\u65b0\u3057\u3044\u5f15\u304d\u7de0\u3081\u30af\u30ea\u30fc\u30e0\u306e200\u30ad\u30ed\u306e\u30d1\u30a4\u30ed\u30c3\u30c8\u30d0\u30c3\u30c1\u3092\u5b8c\u6210\u3055\u305b\u305f\u3070\u304b\u308a\u3067\u3057\u305f\u3002\u305d\u306e\u51e6\u65b9\u306f\u63a5\u7740\u5264\u306e\u3088\u3046\u306a\u611f\u89e6\u3067\u3057\u305f\u3002\u30c6\u30b9\u30bf\u30fc\u305f\u3061\u306f\u3001\u808c\u306b\u6b8b\u308b\u3079\u305f\u3064\u304d\u3068\u606f\u82e6\u3057\u3044\u4ed5\u4e0a\u304c\u308a\u304c\u5acc\u3044\u3067\u3057\u305f\u3002\u79c1\u306f\u5f7c\u306b\u3001\u91cd\u3044\u30dd\u30ea\u30de\u30fc\u3092\u3084\u3081\u308b\u3088\u3046\u306b\u4f1d\u3048\u307e\u3057\u305f\u3002\u7fcc\u671d\u3001\u5f7c\u306e\u5316\u5b66\u8005\u306b\u5f53\u793e\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30d7\u30ed\u30d4\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30d4\u30e9\u30f3\u30c8\u30ea\u30aa\u30fc\u30eb\u6db2\u4f53\u306e\u30dc\u30c8\u30eb\u3092\u9001\u308a\u307e\u3057\u305f\u3002\u5f7c\u306e\u6b21\u306e\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u306f\u3001\u307e\u308b\u3067\u7d14\u7c8b\u306a\u30b7\u30eb\u30af\u306e\u3088\u3046\u306a\u611f\u89e6\u3067\u3057\u305f\u3002\u30c6\u30b9\u30bf\u30fc\u30d1\u30cd\u30eb\u306f\u305d\u308c\u3092\u7d76\u8cdb\u3057\u307e\u3057\u305f\u3002<\/p>

\u79c1\u306f4\u5e74\u9593\u3001\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u5316\u7ca7\u54c1\u30d6\u30e9\u30f3\u30c9\u306b\u6709\u52b9\u6210\u5206\u3092\u8ca9\u58f2\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u51e6\u65b9\u8005\u304c\u540c\u3058\u7f60\u306b\u7e70\u308a\u8fd4\u3057\u9665\u308b\u306e\u3092\u898b\u3066\u304d\u307e\u3057\u305f\u3002\u5f7c\u3089\u306f\u5f37\u529b\u306a\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u52b9\u679c\u3092\u6c42\u3081\u3066\u3001\u808c\u306b\u523a\u6fc0\u306e\u5f37\u3044\u9178\u3084\u3079\u305f\u3064\u304f\u30da\u30d7\u30c1\u30c9\u3092\u904e\u5270\u306b\u914d\u5408\u3057\u307e\u3059\u3002\u6d88\u8cbb\u8005\u306f\u3075\u3063\u304f\u3089\u3068\u3057\u305f\u5f3e\u529b\u306e\u3042\u308b\u808c\u3092\u6c42\u3081\u3066\u3044\u307e\u3059\u304c\u3001\u91cd\u304f\u3066\u4e0d\u5feb\u306a\u30af\u30ea\u30fc\u30e0\u3092\u5857\u308b\u3053\u3068\u3092\u62d2\u5426\u3057\u307e\u3059\u3002<\/p>

\u30d2\u30c9\u30ed\u30ad\u30b7\u30d7\u30ed\u30d4\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30d4\u30e9\u30f3\u30c8\u30ea\u30aa\u30fc\u30eb\u306f\u3001\u767a\u97f3\u3059\u308b\u306e\u304c\u60aa\u5922\u306e\u3088\u3046\u306b\u805e\u3053\u3048\u307e\u3059\u3002\u696d\u754c\u3067\u306f\u5358\u306b\u7a76\u6975\u306e\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u30b7\u30e5\u30ac\u30fc\u3068\u547c\u3070\u308c\u3066\u3044\u307e\u3059\u3002\u300c\u30b0\u30ea\u30b3\u30b5\u30df\u30ce\u30b0\u30ea\u30ab\u30f3\u5408\u6210\u4fc3\u9032\u300d\u306e\u3088\u3046\u306a\u5b66\u8853\u7528\u8a9e\u306f\u3084\u3081\u307e\u3057\u3087\u3046\u3002\u4eba\u9593\u306e\u9854\u3067\u5b9f\u969b\u306b\u4f55\u3092\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u305d\u308c\u306f\u7d30\u80de\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc\u306e\u3088\u3046\u306b\u6a5f\u80fd\u3057\u307e\u3059\u3002\u305d\u308c\u306f\u808c\u306e\u6df1\u3044\u5c64\u306b\u6f5c\u308a\u8fbc\u307f\u307e\u3059\u3002\u305d\u308c\u306f\u3042\u306a\u305f\u306e\u808c\u306b\u81ea\u8eab\u306e\u5929\u7136\u306e\u4fdd\u6c34\u30b9\u30dd\u30f3\u30b8\u3092\u751f\u6210\u3059\u308b\u3088\u3046\u306b\u4f1d\u3048\u307e\u3059\u3002\u305d\u308c\u306f\u7d30\u80de\u306e\u8db3\u5834\u3092\u5185\u5074\u304b\u3089\u518d\u69cb\u7bc9\u3057\u307e\u3059\u3002\u3042\u306a\u305f\u306e\u808c\u306f\u81ea\u7136\u306b\u30b7\u30ef\u3092\u62bc\u3057\u51fa\u3057\u307e\u3059\u3002<\/p>

\u8abf\u9054\u30de\u30cd\u30fc\u30b8\u30e3\u30fc\u306f\u3001\u4f9b\u7d66\u5951\u7d04\u306b\u3064\u3044\u3066\u8a71\u3057\u5408\u3046\u524d\u306b\u3001\u5e38\u306b\u751f\u306e\u5206\u6790\u8a3c\u660e\u66f8\uff08COA\uff09\u30c7\u30fc\u30bf\u3092\u8981\u6c42\u3057\u307e\u3059\u3002\u30cf\u30fc\u30c9\u30c7\u30fc\u30bf\u306f\u8cfc\u5165\u3092\u30b7\u30f3\u30d7\u30eb\u306b\u3057\u307e\u3059\u3002\u5f53\u793e\u306e\u76f4\u63a5\u5de5\u5834\u4f9b\u7d66\u304c\u3001\u6a19\u6e96\u7684\u306a\u30b9\u30dd\u30c3\u30c8\u5e02\u5834\u306e\u30aa\u30d7\u30b7\u30e7\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u3069\u306e\u3088\u3046\u306b\u512a\u308c\u3066\u3044\u308b\u304b\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>

\u30d1\u30e9\u30e1\u30fc\u30bf<\/strong><\/td>\u6a19\u6e96\u53d6\u5f15\u30b0\u30ec\u30fc\u30c9<\/strong><\/td>\u5f53\u793e\u306e\u30d7\u30ec\u30df\u30a2\u30e0\u30a2\u30af\u30c6\u30a3\u30d6\u30ea\u30ad\u30c3\u30c9<\/strong><\/td>\u8a66\u9a13\u65b9\u6cd5<\/strong><\/td><\/tr><\/thead>
\u5916\u89b3<\/td>\u9ec4\u8272\u307f\u304c\u304b\u3063\u305f\u6fc1\u3063\u305f\u6db2\u4f53<\/td>\u7121\u8272\u304b\u3089\u6de1\u9ec4\u8272\u306e\u900f\u660e\u306a\u6db2\u4f53<\/td>\u76ee\u8996<\/td><\/tr>
\u6709\u52b9\u6210\u5206\u542b\u6709\u91cf<\/td>< 30.0%<\/td>>= 30.0%<\/td>HPLC<\/td><\/tr>
pH \u5024<\/td>4.0 – 5.0<\/td>5.5 – 7.5<\/td>pH\u30e1\u30fc\u30bf\u30fc<\/td><\/tr>
\u91cd\u91d1\u5c5e<\/td>< 20 ppm<\/td>< 10 ppm<\/td>ICP-MS<\/td><\/tr><\/tbody><\/table><\/figure>

\u5916\u89b3\u306e\u884c\u3092\u3088\u304f\u898b\u3066\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30b9\u30bf\u30eb\u306e\u3088\u3046\u306b\u900f\u660e\u306a\u6db2\u4f53\u306f\u3001\u3042\u306a\u305f\u306e\u7f8e\u7684\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u5927\u5e45\u306b\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u5b89\u4fa1\u3067\u7d14\u5ea6\u306e\u4f4e\u3044\u6750\u6599\u306b\u306f\u3001\u88fd\u9020\u71b1\u3067\u9178\u5316\u3059\u308b\u4e0d\u7d14\u7269\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u9ad8\u4fa1\u306a\u767d\u3044\u9ad8\u7d1a\u30af\u30ea\u30fc\u30e0\u304c\u6642\u9593\u306e\u7d4c\u904e\u3068\u3068\u3082\u306b\u6c5a\u3044\u9ec4\u8272\u306b\u5909\u8272\u3057\u307e\u3059\u3002<\/p>

\u3053\u306e\u6210\u5206\u3092\u30d9\u30f3\u30c1\u3067\u3069\u306e\u3088\u3046\u306b\u3046\u307e\u304f\u6271\u3044\u307e\u3059\u304b\uff1f\u305d\u308c\u306f\u975e\u5e38\u306b\u6c34\u6eb6\u6027\u3067\u3001\u51e6\u65b9\u304c\u4fe1\u3058\u3089\u308c\u306a\u3044\u307b\u3069\u7c21\u5358\u3067\u3059\u3002\u51e6\u7406\u6e29\u5ea6\u306b\u6ce8\u610f\u3059\u308b\u3060\u3051\u3067\u6e08\u307f\u307e\u3059\u3002<\/p>

\u88fd\u54c1\u30d5\u30a9\u30fc\u30de\u30c3\u30c8<\/strong><\/td>\u63a8\u5968\u4f7f\u7528\u91cf<\/strong><\/td>\u6700\u9069\u306a\u51e6\u7406<\/strong><\/td>\u76ee\u6a19\u3068\u3059\u308b\u52b9\u679c<\/strong><\/td><\/tr><\/thead>
\u30c7\u30a3\u30fc\u30d7\u30ea\u30f3\u30af\u30eb\u30bb\u30e9\u30e0<\/td>5.0% – 10.0%<\/td>\u51b7\u6c34\u76f8\u306b\u76f4\u63a5\u6dfb\u52a0<\/td>\u6df1\u3044\u69cb\u9020\u7684\u306a\u30e9\u30a4\u30f3\u3092\u3075\u3063\u304f\u3089\u3055\u305b\u307e\u3059<\/td><\/tr>
\u30d0\u30a6\u30f3\u30b7\u30fc\u30a2\u30a4\u30af\u30ea\u30fc\u30e0<\/td>3.0% – 5.0%<\/td>\u30af\u30fc\u30eb\u30c0\u30a6\u30f3\u4e2d\uff08< 45 C\uff09\u306b\u7d44\u307f\u8fbc\u3080<\/td>\u808c\u819a\u7d30\u7dfb\u7684\u773c\u4e0b\u808c\u819a<\/td><\/tr>
\u5c4f\u969c\u91cd\u5851\u4e73\u6db2<\/td>2.0% – 4.0%<\/td>\u7121\u7e2b\u878d\u5165\u6c34\u6027\u57fa\u5e95<\/td>\u808c\u5168\u4f53\u306e\u5bc6\u5ea6\u3092\u9ad8\u3081\u307e\u3059<\/td><\/tr><\/tbody><\/table><\/figure>

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