{"id":14563,"date":"2026-05-25T08:27:05","date_gmt":"2026-05-25T08:27:05","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=14563"},"modified":"2026-05-25T08:27:07","modified_gmt":"2026-05-25T08:27:07","slug":"totarol-factory-scale-production-of-premium-bio-actives-for-high-performance-cosmetics","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/ja\/totarol-factory-scale-production-of-premium-bio-actives-for-high-performance-cosmetics\/","title":{"rendered":"\u30c8\u30bf\u30ed\u30fc\u30eb\u5de5\u5834\uff1a\u9ad8\u6027\u80fd\u5316\u7ca7\u54c1\u5411\u3051\u30d7\u30ec\u30df\u30a2\u30e0\u30d0\u30a4\u30aa\u30a2\u30af\u30c6\u30a3\u30d6\u306e\u30b9\u30b1\u30fc\u30eb\u751f\u7523"},"content":{"rendered":"

\u73fe\u4ee3\u306e\u30b9\u30ad\u30f3\u30b1\u30a2\u304a\u3088\u3073\u30d1\u30fc\u30bd\u30ca\u30eb\u30b1\u30a2\u696d\u754c\u3067\u306f\u3001\u5316\u7ca7\u54c1\u30d6\u30e9\u30f3\u30c9\u306f\u52b9\u679c\u306e\u9ad8\u3044\u6210\u5206\u3060\u3051\u3067\u306a\u304f\u3001\u6280\u8853\u7684\u306a\u7cbe\u5ea6\u3068\u53b3\u683c\u306a\u54c1\u8cea\u57fa\u6e96\u306b\u57fa\u3065\u3044\u305f\u30b5\u30d7\u30e9\u30a4\u30c1\u30a7\u30fc\u30f3\u3092\u6c42\u3081\u3066\u3044\u307e\u3059\u3002\u5148\u9032\u7684\u306a \u30c8\u30bf\u30ed\u30fc\u30eb\u5de5\u5834<\/mark><\/a> \u3068\u76f4\u63a5\u63d0\u643a\u3059\u308b\u3053\u3068\u306f\u3001\u6b21\u4e16\u4ee3\u306e\u751f\u7269\u6d3b\u6027\u539f\u6599\u306e\u5b89\u5b9a\u4f9b\u7d66\u3092\u78ba\u4fdd\u3057\u3088\u3046\u3068\u3059\u308b\u30b0\u30ed\u30fc\u30d0\u30eb\u4f01\u696d\u306b\u3068\u3063\u3066\u4e0d\u53ef\u6b20\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u3001C20H30O\u3068\u79d1\u5b66\u7684\u306b\u5b9a\u7fa9\u3055\u308c\u308b\u6709\u6a5f\u30b8\u30c6\u30eb\u30da\u30ce\u30a4\u30c9\u30d5\u30a7\u30ce\u30fc\u30eb\u3067\u3042\u308a\u3001\u30cb\u30e5\u30fc\u30b8\u30fc\u30e9\u30f3\u30c9\u306e\u30c8\u30bf\u30e9\u6728\u306e\u518d\u751f\u5fc3\u6750\u304b\u3089\u5206\u96e2\u3055\u308c\u307e\u3059\u3002\u9ad8\u5ea6\u306a\u5de5\u696d\u7684\u5206\u96e2\u65b9\u6cd5\u3067\u88fd\u9020\u3055\u308c\u305f\u3053\u306e\u975e\u5e38\u306b\u5b89\u5b9a\u3057\u305f\u7d50\u6676\u6027\u5316\u5408\u7269\u306f\u3001\u5fae\u751f\u7269\u306e\u8105\u5a01\u3084\u9178\u5316\u7684\u306a\u7d30\u80de\u52a3\u5316\u306b\u5bfe\u3057\u3066\u6bd4\u985e\u306e\u306a\u3044\u9632\u5fa1\u529b\u3092\u63d0\u4f9b\u3057\u3001\u30d7\u30ec\u30df\u30a2\u30e0\u306a\u30c0\u30fc\u30e2\u30b3\u30b9\u30e1\u30c6\u30a3\u30af\u30b9\u306e\u57fa\u76e4\u8cc7\u7523\u3068\u3057\u3066\u306e\u5730\u4f4d\u3092\u78ba\u7acb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>

\u5de5\u696d\u7684\u62bd\u51fa\u3068\u6280\u8853\u7684\u54c1\u8cea\u30d1\u30e9\u30e1\u30fc\u30bf<\/h2>

\u539f\u6599\u304c\u5408\u6210\u5316\u5b66\u7269\u8cea\u306b\u3088\u308b\u6c5a\u67d3\u306e\u30ea\u30b9\u30af\u306a\u3057\u306b\u6700\u5927\u306e\u751f\u7269\u5b66\u7684\u52b9\u529b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3092\u4fdd\u8a3c\u3059\u308b\u305f\u3081\u306b\u3001\u4e16\u754c\u30af\u30e9\u30b9\u306e\u88fd\u9020\u65bd\u8a2d\u3067\u306f\u30b0\u30ea\u30fc\u30f3\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\u3001\u7279\u306b\u8d85\u81e8\u754c\u4e8c\u9178\u5316\u70ad\u7d20\uff08CO2\uff09\u62bd\u51fa\u6280\u8853\u3092\u5229\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u6d3b\u6027\u30b8\u30c6\u30eb\u30da\u30ce\u30a4\u30c9\u5206\u5b50\u306e\u8907\u96d1\u306a\u5316\u5b66\u69cb\u9020\u3092\u640d\u50b7\u3057\u305f\u308a\u3001\u6709\u5bb3\u306a\u6709\u6a5f\u6eb6\u5264\u6b8b\u7559\u7269\u3092\u6b8b\u3057\u305f\u308a\u3059\u308b\u3053\u3068\u306a\u304f\u5206\u96e2\u3057\u307e\u3059\u3002\u4ee5\u4e0b\u306e\u6a19\u6e96\u7684\u306a\u6280\u8853\u4ed5\u69d8\u306f\u3001\u30d7\u30ec\u30df\u30a2\u30e0\u5316\u7ca7\u54c1\u88fd\u9020\u306b\u5fc5\u8981\u306a\u5206\u6790\u30d9\u30f3\u30c1\u30de\u30fc\u30af\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002<\/p>

\u4ed5\u69d8\u30d1\u30e9\u30e1\u30fc\u30bf<\/strong><\/td>\u76ee\u6a19\u6a19\u6e96\u5024 \/ \u5024<\/strong><\/td>\u8a66\u9a13\u65b9\u6cd5<\/strong><\/td><\/tr><\/thead>
\u5916\u89b3<\/td>\u6de1\u9ec4\u8272\u306e\u7d50\u6676\u6027\u7c89\u672b<\/td>\u76ee\u8996\u691c\u67fb<\/td><\/tr>
\u30a2\u30c3\u30bb\u30a4\uff08\u30c8\u30bf\u30ed\u30fc\u30eb\u542b\u6709\u91cf\uff09<\/td>99.0%\u4ee5\u4e0a<\/td>HPLC<\/td><\/tr>
\u878d\u70b9<\/td>126.0\uff5e132.0\u2103<\/td>\u6bdb\u7d30\u7ba1\u6cd5<\/td><\/tr>
\u4e7e\u71e5\u6e1b\u91cf<\/td><= 0.5%<\/td>\u91cd\u91cf\u6cd5<\/td><\/tr>
\u91cd\u91d1\u5c5e\uff08Pb\u3068\u3057\u3066\uff09<\/td>10 ppm\u4ee5\u4e0b<\/td>ICP-MS<\/td><\/tr>
\u30d2\u7d20 (As)<\/td><= 2 ppm<\/td>ICP-MS<\/td><\/tr>
\u7dcf\u83cc\u6570<\/td><= 100 cfu\/g<\/td>USP \/ \u5fae\u751f\u7269<\/td><\/tr>
\u9175\u6bcd\u83cc\u3068\u30ab\u30d3<\/td><= 10 cfu\/g<\/td>USP \/ \u5fae\u751f\u7269<\/td><\/tr><\/tbody><\/table><\/figure>

\u30c7\u30e5\u30a2\u30eb\u751f\u4f53\u30e1\u30ab\u30cb\u30ba\u30e0\uff1a\u7d30\u80de\u4fdd\u8b77\u3068\u6a19\u7684\u5fae\u751f\u7269\u9632\u5fa1<\/h2>
\"\u30c8\u30bf\u30ed\u30fc\u30eb\u5de5\u5834\"<\/a><\/figure><\/div>

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  1. \u7cbe\u5bc6\u306a\u819c\u7834\u58ca\u6297\u83cc\u4f5c\u7528<\/strong>: \u5f93\u6765\u306e\u5408\u6210\u6297\u83cc\u5264\u306f\u3001\u5065\u5eb7\u306a\u76ae\u819a\u5e38\u5728\u83cc\u53e2\u3092\u5265\u304e\u53d6\u308a\u3001\u30d0\u30ea\u30a2\u306e\u523a\u6fc0\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3088\u304f\u3042\u308a\u307e\u3059\u3002\u5bfe\u7167\u7684\u306b\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u7279\u5b9a\u306e\u76ae\u819a\u5fae\u7d30\u751f\u7269\u3092\u6a19\u7684\u3068\u3057\u3001\u975e\u5e38\u306b\u4f4e\u3044\u6700\u5c0f\u767a\u80b2\u963b\u6b62\u6fc3\u5ea6\u30ad\u30cd\u30c6\u30a3\u30af\u30b9\u3092\u793a\u3057\u307e\u3059\u3002 \u30a2\u30af\u30cd\u83cc<\/em> \u304a\u3088\u3073 \u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc<\/em>\u7d30\u83cc\u7d30\u80de\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306b\u5b89\u5168\u306b\u6d78\u900f\u3057\u3001\u8840\u6f3f\u819c\u96fb\u4f4d\u3092\u7834\u58ca\u3057\u3001\u5468\u56f2\u306e\u751f\u4f53\u7d44\u7e54\u3092\u523a\u6fc0\u3059\u308b\u3053\u3068\u306a\u304f\u547c\u5438\u96fb\u5b50\u4f1d\u9054\u3092\u963b\u5bb3\u3057\u307e\u3059\u3002<\/li>\n\n
  2. \u512a\u308c\u305f\u30e9\u30b8\u30ab\u30eb\u9664\u53bb\u3068\u8102\u8cea\u4fdd\u8b77<\/strong>: \u4eba\u9593\u306e\u76ae\u8102\u9178\u5316\u306f\u3001\u6bdb\u7a74\u306e\u8a70\u307e\u308a\u3068\u708e\u75c7\u6027\u76ae\u819a\u75c5\u5909\u306e\u4e21\u65b9\u306e\u4e3b\u8981\u306a\u89e6\u5a92\u3067\u3059\u3002\u79d1\u5b66\u7684\u30c7\u30fc\u30bf\u306b\u3088\u308b\u3068\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u03b1-\u30c8\u30b3\u30d5\u30a7\u30ed\u30fc\u30eb\uff08\u30d3\u30bf\u30df\u30f3E\uff09\u3068\u6bd4\u8f03\u3057\u3066\u7d047\u500d\u306e\u6297\u9178\u5316\u52b9\u7387\u3092\u767a\u63ee\u3057\u307e\u3059\u3002\u30da\u30eb\u30aa\u30ad\u30b7\u30e9\u30b8\u30ab\u30eb\u3092\u7a4d\u6975\u7684\u306b\u6355\u6349\u3059\u308b\u3053\u3068\u3067\u3001\u30b9\u30af\u30ef\u30ec\u30f3\u306e\u5206\u89e3\u3092\u9632\u304e\u3001\u74b0\u5883\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u76ae\u819a\u306e\u69cb\u9020\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4fdd\u8b77\u3057\u307e\u3059\u3002<\/li><\/ol>

    \u7523\u696d\u5fdc\u7528\u3068\u81e8\u5e8a\u30c7\u30fc\u30bf<\/strong>: 0.1%\u304b\u30890.5%\u306e\u9ad8\u7d14\u5ea6\u5de5\u5834\u751f\u7523\u30c8\u30bf\u30ed\u30fc\u30eb\u3092\u914d\u5408\u3057\u305f\u5916\u7528\u4e73\u5264\u3092\u7528\u3044\u305fin vivo\u76ae\u819a\u8a66\u9a13\u3067\u306f\u300128\u65e5\u9593\u306e\u8a66\u9a13\u30b5\u30a4\u30af\u30eb\u3067\u8868\u9762\u76ae\u8102\u84c4\u7a4d\u91cf\u304c\u6700\u592730%\u6e1b\u5c11\u3057\u3001\u30cb\u30ad\u30d3\u75c5\u5909\u4f53\u7a4d\u304c16%\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u6307\u6a19\u306f\u3001\u5f93\u6765\u306e\u5408\u6210\u5316\u5b66\u54c1\u30aa\u30d7\u30b7\u30e7\u30f3\u306b\u5bfe\u3059\u308b\u512a\u4f4d\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p><\/blockquote>

    \u30b0\u30ed\u30fc\u30d0\u30eb\u30b3\u30b9\u30e1\u30c6\u30a3\u30c3\u30af\u5fdc\u7528\u4e8b\u4f8b\u3068\u81e8\u5e8a\u30b1\u30fc\u30b9\u30b9\u30bf\u30c7\u30a3<\/h2>

    \u5929\u7136\u4fdd\u5b58\u30b7\u30b9\u30c6\u30e0\u304b\u3089\u81e8\u5e8a\u30b0\u30ec\u30fc\u30c9\u306e\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u30b9\u30ad\u30f3\u30b1\u30a2\u307e\u3067\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u306e\u5de5\u5834\u30ec\u30d9\u30eb\u3067\u306e\u751f\u7523\u306f\u3001\u56fd\u969b\u7684\u306a\u30af\u30ea\u30fc\u30f3\u30d3\u30e5\u30fc\u30c6\u30a3\u30fc\u306e\u5206\u91ce\u3067\u591a\u69d8\u306a\u30bb\u30af\u30bf\u30fc\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>

    \u75c7\u4f8b\u7814\u7a76A\uff1a\u30af\u30ea\u30fc\u30f3\u30e9\u30d9\u30eb\u306e\u30cb\u30ad\u30d3\u6cbb\u7642\u30b9\u30ad\u30f3\u30b1\u30a2\u30b7\u30b9\u30c6\u30e0<\/strong><\/p>

    \u3042\u308b\u30b0\u30ed\u30fc\u30d0\u30eb\u81e8\u5e8a\u30d6\u30e9\u30f3\u30c9\u306f\u3001\u30c8\u30ea\u30af\u30ed\u30b5\u30f3\u306a\u3069\u306e\u5f37\u529b\u306a\u5408\u6210\u6297\u83cc\u5264\u306b\u4ee3\u308f\u308b\u30af\u30ea\u30fc\u30f3\u306a\u4ee3\u66ff\u54c1\u3092\u6c42\u3081\u3066\u3044\u307e\u3057\u305f\u3002\u7d14\u5ea60.2%\u306e\u30c8\u30bf\u30ed\u30fc\u30eb\u30d1\u30a6\u30c0\u30fc\u3092\u914d\u5408\u3057\u305f\u30bf\u30fc\u30b2\u30c3\u30c8\u30cb\u30ad\u30d3\u56de\u5fa9\u30af\u30ea\u30fc\u30e0\u3092\u958b\u767a\u3057\u3001\u30d6\u30e9\u30f3\u30c9\u306f\u4eba\u9593\u306e\u30b3\u30db\u30fc\u30c8\u3092\u5bfe\u8c61\u306b6\u9031\u9593\u306e\u89b3\u5bdf\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u808c\u5168\u4f53\u306e\u5747\u4e00\u6027\u304c15%\u6539\u5584\u3055\u308c\u3001\u708e\u75c7\u6027\u7d05\u6591\u304c\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u307e\u3057\u305f\u304c\u3001\u63a5\u89e6\u76ae\u819a\u708e\u3001\u76ae\u819a\u306e\u5265\u304c\u308c\u3001\u8102\u8cea\u30d0\u30ea\u30a2\u306e\u4f4e\u4e0b\u306e\u5831\u544a\u306f\u30bc\u30ed\u3067\u3057\u305f\u3002<\/p>

    \u75c7\u4f8b\u7814\u7a76B\uff1a\u30cf\u30a4\u30a8\u30f3\u30c9\u306e\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u3068\u69cb\u9020\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4fdd\u8b77<\/strong><\/p>

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