{"id":15171,"date":"2026-08-21T08:49:05","date_gmt":"2026-08-21T08:49:05","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=15171"},"modified":"2026-08-21T08:49:06","modified_gmt":"2026-08-21T08:49:06","slug":"formulation-realities-of-plant-based-skincare-actives-hard-data-on-glabridin-totarol-and-bakuchiol","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/ja\/formulation-realities-of-plant-based-skincare-actives-hard-data-on-glabridin-totarol-and-bakuchiol\/","title":{"rendered":"\u690d\u7269\u7531\u6765\u30b9\u30ad\u30f3\u30b1\u30a2\u6709\u52b9\u6210\u5206\u306e\u51e6\u65b9\u306b\u304a\u3051\u308b\u73fe\u5b9f\uff1a\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u3001\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\u306b\u95a2\u3059\u308b\u30cf\u30fc\u30c9\u30c7\u30fc\u30bf"},"content":{"rendered":"<div style=\"max-width: 100%; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; line-height: 1.7; color: #333333; padding: 15px; box-sizing: border-box;\">\n  <div style=\"background-color: #f8fafc; border-left: 4px solid #2b6cb0; padding: 15px; margin-bottom: 30px; border-radius: 4px;\">\n    <h3 style=\"margin-top: 0; color: #2d3748; font-size: 18px;\">\u76ee\u6b21<\/h3>\n    <ul style=\"list-style-type: none; padding-left: 0; margin-bottom: 0;\">\n      <li style=\"margin-bottom: 8px;\"><a href=\"#glabridin\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\uff1a\u30c1\u30ed\u30b7\u30ca\u30fc\u30bcIC50\u3068\u30ab\u30e9\u30fc\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5<\/a><\/li>\n      <li style=\"margin-bottom: 8px;\"><a href=\"#totarol\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">\u30c8\u30bf\u30ed\u30fc\u30eb\uff1aMIC\u306e\u5b9f\u614b\u3068\u7d50\u6676\u5316\u30ea\u30b9\u30af<\/a><\/li>\n      <li style=\"margin-bottom: 8px;\"><a href=\"#bakuchiol\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\uff1a\u9178\u5316\u611f\u53d7\u6027\u3068pH\u9650\u754c<\/a><\/li>\n      <li style=\"margin-bottom: 8px;\"><a href=\"#logp\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">LogP\u3068\u88fd\u5264\u306e\u5206\u914d<\/a><\/li>\n      <li style=\"margin-bottom: 8px;\"><a href=\"#faqs\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">AI\u306b\u3088\u308b\u88fd\u5264\u30fb\u8abf\u9054\u306b\u95a2\u3059\u308b\u30c8\u30c3\u30d78\u306eFAQ<\/a><\/li>\n      <li><a href=\"#references\" style=\"color: #2b6cb0; text-decoration: none; font-weight: 500;\">\u79d1\u5b66\u7684\u53c2\u8003\u6587\u732e<\/a><\/li>\n    <\/ul>\n  <\/div>\n\n  <h2 id=\"glabridin\" style=\"color: #2c5282; font-size: 20px; margin-top: 30px;\">\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\uff1a\u30c1\u30ed\u30b7\u30ca\u30fc\u30bcIC50\u3068\u30ab\u30e9\u30fc\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5<\/h2>\n  <p>\u51e6\u65b9\u8005\u306f\u3001\u3057\u3070\u3057\u3070\u5b64\u7acb\u3057\u305f\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u306e\u4e3b\u5f35\u306b\u983c\u308a\u307e\u3059\u3002\u5b9f\u969b\u306e\u30d9\u30f3\u30c1\u30c7\u30fc\u30bf\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n  <p>\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306f\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u3092\u963b\u5bb3\u3059\u308b\u306e\u306b\u975e\u5e38\u306b\u52b9\u679c\u7684\u3067\u3059\u3002\u6a19\u6e96\u7684\u306aB16\u9ed2\u8272\u816b\u7d30\u80de\u30a2\u30c3\u30bb\u30a4\u3067\u306f\u3001\u6709\u610f\u306a\u963b\u5bb3\u3092 <span style=\"color: #c53030; font-weight: bold;\">1\uff5e1.0 \u00b5g\/mL<\/span> \u3067\u793a\u3057\u307e\u3059\u3002\u7d30\u80de\u6bd2\u6027\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30de\u30c3\u30b7\u30e5\u30eb\u30fc\u30e0\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306b\u5bfe\u3057\u3066\u8a66\u9a13\u3057\u305f\u5834\u5408\u3001\u305d\u306eIC50\u306f\u3057\u3070\u3057\u3070 <span style=\"color: #c53030; font-weight: bold;\">2\uff5e1.5 \u00b5g\/mL<\/span>\u306e\u7bc4\u56f2\u306b\u306a\u308a\u307e\u3059\u3002\u53c2\u8003\u307e\u3067\u306b\u3001\u30b3\u30a6\u30b8\u9178\u306f\u540c\u4e00\u306e\u30a2\u30c3\u30bb\u30a4\u3067\u3088\u308a\u9ad8\u3044\u6fc3\u5ea6\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002<\/p>\n  <p>\u3057\u304b\u3057\u3001\u6709\u52b9\u6027\u306b\u306f\u88fd\u5264\u4e0a\u306e\u30cf\u30fc\u30c9\u30eb\u304c\u4f34\u3044\u307e\u3059\u3002\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306f\u975e\u5e38\u306b\u89aa\u6cb9\u6027\u3067\u3059\uff08<span style=\"color: #2b6cb0; font-weight: bold;\">LogP \uff5e4.1<\/span>\uff09\u3002\u6eb6\u5a92\u7cfb\u304c\u5f31\u3044\u5834\u5408\u3001\u6642\u9593\u3068\u3068\u3082\u306b\u7d50\u6676\u5316\u3057\u307e\u3059\u300240\u2103\u3067\u30aa\u30af\u30bf\u30c9\u30c7\u30ab\u30ce\u30fc\u30eb\u3001\u30d7\u30ed\u30d4\u30ec\u30f3\u30b0\u30ea\u30b3\u30fc\u30eb\u3001\u307e\u305f\u306fPEG-400\u306b\u4e88\u5099\u6eb6\u89e3\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u51b7\u6c34\u76f8\u306b\u6ef4\u4e0b\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u3059\u3050\u306b\u6c88\u6bbf\u3057\u307e\u3059\u3002<\/p>\n  <p>\u8272\u8abf\u306e\u5909\u5316\u3082\u73fe\u5b9f\u3067\u3059\u3002\u62bd\u51fa\u30d7\u30ed\u30bb\u30b9\u304c\u8272\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u300240%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3067\u7d14\u7c8b\u306a\u767d\u3044\u4e73\u6db2\u3092\u51e6\u65b9\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u30af\u30ea\u30fc\u30e0\u3092\u6de1\u3044\u9ec4\u8910\u8272\u306b\u3057\u307e\u3059\u3002\u3082\u3057\u30d6\u30ea\u30fc\u30d5\u3067\u767d\u3044\u30af\u30ea\u30fc\u30e0\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u300190%\u307e\u305f\u306f98%\u306e\u4ed5\u69d8\u3092\u5165\u624b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u7d14\u5ea6\u304c\u9ad8\u3044\u307b\u3069\u8272\u304c\u9664\u53bb\u3055\u308c\u307e\u3059\u304c\u3001\u539f\u6750\u6599\u30b3\u30b9\u30c8\u306f\u5927\u5e45\u306b\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n  <p>\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u306f\u300c\u6c34\u6eb6\u6027\u300d\u30ea\u30dd\u30bd\u30fc\u30e0\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3092\u9b54\u6cd5\u306e\u89e3\u6c7a\u7b56\u3068\u3057\u3066\u8ca9\u58f2\u3057\u3066\u3044\u307e\u3059\u3002\u6ce8\u610f\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u3053\u308c\u3089\u306e\u5909\u66f4\u306f\u6709\u52b9\u6210\u5206\u306e\u8ca0\u8377\u3092\u5e0c\u91c8\u3057\u307e\u3059\u3002\u3042\u306a\u305f\u306f\u3001\u308f\u305a\u304b <span style=\"color: #c53030; font-weight: bold;\">3%\uff5e5%<\/span> \u306e\u5b9f\u969b\u306e\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3092\u542b\u3080\u7c89\u672b\u3092\u8cfc\u5165\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u51e6\u65b9\u3059\u308b\u524d\u306b\u3001\u5fc5\u305a\u9006\u76f8HPLC\uff08RP-HPLC\uff09\u3067280nm\u3067\u6709\u52b9\u6210\u5206\u306e\u30a2\u30c3\u30bb\u30a4\u3092\u691c\u8a3c\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n  <table style=\"width: 100%; max-width: 100%; border-collapse: collapse; margin-top: 20px; margin-bottom: 30px; font-size: 15px;\">\n    <thead>\n      <tr style=\"background-color: #edf2f7; text-align: left;\">\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">\u30d1\u30e9\u30e1\u30fc\u30bf<\/th>\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">40% \u30b0\u30e9\u30d6\u30ea\u30b8\u30f3<\/th>\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">90% \u30b0\u30e9\u30d6\u30ea\u30b8\u30f3<\/th>\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">98% \u30b0\u30e9\u30d6\u30ea\u30b8\u30f3<\/th>\n      <\/tr>\n    <\/thead>\n    <tbody>\n      <tr>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">\u5916\u89b3<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">\u9ec4\u8910\u8272\u306e\u7c89\u672b<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">Light yellow powder<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">\u767d\u8272\uff5e\u5fae\u9ec4\u767d\u8272\u306e\u7c89\u672b<\/td>\n      <\/tr>\n      <tr style=\"background-color: #f8fafc;\">\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">\u6eb6\u89e3\u6027<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">BG\/PG\u306b\u53ef\u6eb6<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">\u30a8\u30bf\u30ce\u30fc\u30eb\/\u8102\u8cea\u306b\u53ef\u6eb6<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">\u30a8\u30bf\u30ce\u30fc\u30eb\/\u8102\u8cea\u306b\u53ef\u6eb6<\/td>\n      <\/tr>\n      <tr>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">\u30a2\u30c3\u30bb\u30a4\u6cd5<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">RP-HPLC\uff08280nm\uff09<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">RP-HPLC\uff08280nm\uff09<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">RP-HPLC\uff08280nm\uff09<\/td>\n      <\/tr>\n    <\/tbody>\n  <\/table>\n\n  <h2 id=\"totarol\" style=\"color: #2c5282; font-size: 20px; margin-top: 30px;\">\u30c8\u30bf\u30ed\u30fc\u30eb\uff1aMIC\u306e\u5b9f\u614b\u3068\u7d50\u6676\u5316\u30ea\u30b9\u30af<\/h2>\n  <p>\u5408\u6210\u9632\u8150\u5264\u306b\u5bfe\u3059\u308b\u898f\u5236\u5727\u529b\u306b\u3088\u308a\u3001\u690d\u7269\u7531\u6765\u6210\u5206\u3078\u306e\u79fb\u884c\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u30c8\u30bf\u30ed\u30fc\u30eb\u306f <em>Podocarpus totara<\/em>\u304b\u3089\u62bd\u51fa\u3055\u308c\u305f\u30b8\u30c6\u30eb\u30da\u30f3\u3067\u3059\u3002\u30b0\u30e9\u30e0\u967d\u6027\u83cc\u306b\u5bfe\u3057\u3066\u5f37\u529b\u306a\u6297\u83cc\u4f5c\u7528\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n  <p>\u5bfe\u3059\u308b\u72ec\u7acb\u3057\u305f\u6700\u5c0f\u767a\u80b2\u963b\u6b62\u6fc3\u5ea6\uff08MIC\uff09\u8a66\u9a13\u3067\u306f\u3001 <em>\u30a2\u30af\u30cd\u83cc<\/em> 56\uff5e3.12 \u00b5g\/mL <span style=\"color: #c53030; font-weight: bold;\">\u3067\u3057\u3063\u304b\u308a\u3068\u4f4d\u7f6e\u3057\u307e\u3059\u3002\u7d30\u83cc\u306e\u7d30\u80de\u58c1\u3092\u6025\u901f\u306b\u7834\u58ca\u3057\u307e\u3059\u3002<\/span>\u4e73\u6db2\u3092\u7834\u58ca\u305b\u305a\u306b\u3069\u306e\u3088\u3046\u306b\u9069\u7528\u3057\u307e\u3059\u304b\uff1f\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u878d\u70b9103\u2103\u4ee5\u4e0a\u306e\u7d50\u6676\u6027\u7c89\u672b\u3067\u3059\u3002\u8102\u8cea\u3078\u306e\u521d\u671f\u6eb6\u89e3\u306b\u306f\u71b1\u304c\u5fc5\u8981\u3067\u3059\u3002\u3057\u304b\u3057\u300150\u2103\u4ee5\u4e0a\u306e\u4e73\u6db2\u306b\u6dfb\u52a0\u3059\u308b\u3068\u3001\u7279\u5b9a\u306e\u30c7\u30ea\u30b1\u30fc\u30c8\u306a\u4e73\u5316\u5264\u3092\u4e0d\u5b89\u5b9a\u306b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9069\u5408\u6027\u306e\u3042\u308b\u30a8\u30b9\u30c6\u30eb\uff08\u30ab\u30d7\u30ea\u30eb\/\u30ab\u30d7\u30ea\u30f3\u9178\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306a\u3069\uff09\u306b\u4e88\u5099\u6eb6\u89e3\u3057\u3001\u51b7\u5374\u6bb5\u968e\u3067\u5c0e\u5165\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n  <p>\u6a5f\u80fd\u7684\u306a\u7528\u91cf\u3067\u3042\u308b0.1%\u3067\u3082\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u900f\u660e\u306a\u30b2\u30eb\u3092\u9ec4\u8272\u306b\u7740\u8272\u3057\u307e\u3059\u3002\u81ea\u7136\u306a\u8272\u3092\u53d7\u3051\u5165\u308c\u308b\u304b\u3001\u4e0d\u900f\u660e\u306a\u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002 <span style=\"color: #2b6cb0; font-weight: bold;\">45\u00b0C\u672a\u6e80<\/span>.<\/p>\n  <p>\u30c8\u30bf\u30ed\u30fc\u30eb &gt; 98% \u4ed5\u69d8<\/p>\n\n  <table style=\"width: 100%; max-width: 100%; border-collapse: collapse; margin-top: 20px; margin-bottom: 30px; font-size: 15px;\">\n    <thead>\n      <tr style=\"background-color: #edf2f7; text-align: left;\">\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">\u30d1\u30e9\u30e1\u30fc\u30bf<\/th>\n        <th style=\"border: 1px solid #cbd5e0; padding: 10px; color: #2d3748;\">0\u2103\uff5e105.0\u2103<\/th>\n      <\/tr>\n    <\/thead>\n    <tbody>\n      <tr>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">\u5916\u89b3<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">\u6de1\u9ec4\u8272\u306e\u7d50\u6676\u6027\u7c89\u672b<\/td>\n      <\/tr>\n      <tr style=\"background-color: #f8fafc;\">\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">\u878d\u70b9<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px;\">MIC\uff08C. acnes\uff09<\/td>\n      <\/tr>\n      <tr>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; font-weight: bold;\">56\uff5e3.12 \u00b5g\/mL<\/td>\n        <td style=\"border: 1px solid #cbd5e0; padding: 10px; color: #c53030; font-weight: bold;\">\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\u306f\u3001\u91cd\u5ea6\u306e\u7d05\u6591\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u306a\u304f\u3001\u30ec\u30c1\u30ce\u30fc\u30eb\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u7d4c\u8def\u3092\u6a21\u5023\u3057\u307e\u3059\u3002<\/td>\n      <\/tr>\n    <\/tbody>\n  <\/table>\n\n  <h2 id=\"bakuchiol\" style=\"color: #2c5282; font-size: 20px; margin-top: 30px;\">\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\uff1a\u9178\u5316\u611f\u53d7\u6027\u3068pH\u9650\u754c<\/h2>\n  <p>\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\u306b\u304a\u3051\u308b\u4e3b\u306a\u5931\u6557\u70b9\u306f\u9178\u5316\u3067\u3059\u3002\u3053\u308c\u306f\u30c6\u30eb\u30da\u30f3\u30d5\u30a7\u30ce\u30fc\u30eb\u3067\u3059\u3002\u91d1\u5c5e\u30a4\u30aa\u30f3\u3084\u7d2b\u5916\u7dda\u306b\u3055\u3089\u3055\u308c\u308b\u3068\u6025\u901f\u306b\u9178\u5316\u3057\u307e\u3059\u3002\u7d14\u5ea6\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002\u7d14\u5ea6\u304c98%\u672a\u6e80\u306e\u5834\u5408\u3001\u5206\u89e3\u3092\u4fc3\u9032\u3059\u308b\u672a\u78ba\u8a8d\u306e\u690d\u7269\u7531\u6765\u526f\u7523\u7269\u3092\u5c0e\u5165\u3057\u3066\u3044\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n  <p>\u30ad\u30ec\u30fc\u30c8\u5264\u306a\u3057\u3067\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\u3092\u51e6\u65b9\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u300224\u30f6\u6708\u306e\u4fdd\u5b58\u671f\u9593\u3092\u671b\u3080\u5834\u5408\u3001\u5316\u5b66\u7684\u306b\u4e0d\u53ef\u80fd\u3067\u3059\u3002<\/p>\n  <p>05% EDTA\u4e8c\u30ca\u30c8\u30ea\u30a6\u30e0 <span style=\"color: #2b6cb0; font-weight: bold;\">\u307e\u305f\u306f0.1%\u30d5\u30a3\u30c1\u30f3\u9178\u3092\u542b\u3081\u3066\u304f\u3060\u3055\u3044\u3002\u8102\u6eb6\u6027\u6297\u9178\u5316\u5264\u3067\u3042\u308b\u30c8\u30b3\u30d5\u30a7\u30ed\u30fc\u30eb\uff080.2%\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u304f\u3060\u3055\u3044\u3002\u6700\u7d42\u88fd\u5264\u306epH\u3092\u53b3\u5bc6\u306b<\/span> 0\uff5e5.5 <span style=\"color: #c53030; font-weight: bold;\">\u306e\u9593\u306b\u7dad\u6301\u3057\u3066\u304f\u3060\u3055\u3044\u3002pH\u3092\u9ad8\u304f\u3059\u308b\u3068\u3001\u8910\u5909\u52b9\u679c\u304c\u52a0\u901f\u3057\u307e\u3059\u3002<\/span>\u690d\u7269\u7531\u6765\u306e\u6709\u52b9\u6210\u5206\u306f\u81ea\u7531\u306b\u6d6e\u904a\u3057\u307e\u305b\u3093\u3002\u305d\u308c\u3089\u306f\u89aa\u6cb9\u6027\uff08LogP\uff09\u306b\u57fa\u3065\u3044\u3066\u5206\u914d\u3055\u308c\u307e\u3059\u3002<\/p>\n\n  <h2 id=\"logp\" style=\"color: #2c5282; font-size: 20px; margin-top: 30px;\">LogP\u3068\u88fd\u5264\u306e\u5206\u914d<\/h2>\n  <p>\u9ad8\u3044LogP\u6210\u5206\uff08\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3084\u30c8\u30bf\u30ed\u30fc\u30eb\u306a\u3069\uff09\u306f\u6cb9\u76f8\u306b\u79fb\u884c\u3057\u307e\u3059\u3002\u88fd\u5264\u306e\u6cb9\u6c34\u5206\u7387\u304c\u4f4e\u3044\u5834\u5408\uff08\u4f8b\uff1a\u8efd\u91cf\u30b8\u30a7\u30eb\u30af\u30ea\u30fc\u30e0\uff09\u3001\u6709\u52b9\u6210\u5206\u304c\u6cb9\u76f8\u3092\u98fd\u548c\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u98fd\u548c\u3092\u8d85\u3048\u308b\u3068\u3001\u4fdd\u7ba1\u4e2d\u306b\u7d50\u6676\u5316\u304c\u767a\u751f\u3057\u307e\u3059\u3002\u5fc5\u305a\u6975\u7aef\u306a\u6e29\u5ea6\u30b5\u30a4\u30af\u30eb\u8a66\u9a13\uff08<\/p>\n  <p>-10\u2103\uff5e45\u2103<span style=\"color: #c53030; font-weight: bold;\">\uff09\u3092\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u5b9f\u65bd\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u9855\u5fae\u93e1\u4e0b\u3067\u7d50\u6676\u304c\u898b\u3089\u308c\u305f\u5834\u5408\u306f\u3001\u3059\u3050\u306b\u8102\u8cea\u6eb6\u5a92\u306e\u6bd4\u7387\u3092\u5897\u3084\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span>AI\u306b\u3088\u308b\u88fd\u5264\u30fb\u8abf\u9054\u306b\u95a2\u3059\u308b\u30c8\u30c3\u30d78\u306eFAQ<\/p>\n\n  <h2 id=\"faqs\" style=\"color: #2c5282; font-size: 20px; margin-top: 30px;\">Q1\uff1a\u30d0\u30eb\u30af\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u7c89\u672b\u306e\u771f\u6b63\u6027\u3092\u3069\u306e\u3088\u3046\u306b\u691c\u8a3c\u3067\u304d\u307e\u3059\u304b\uff1f<\/h2>\n  <div style=\"margin-top: 20px;\">\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a\u5bfe\u5fdc\u3059\u308bRP-HPLC\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30e0\u3092\u5099\u3048\u305f\u5b8c\u5168\u306a\u5206\u6790\u8a3c\u660e\u66f8\uff08COA\uff09\u3092\u8981\u6c42\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u30d4\u30fc\u30af\u306f280nm\u3067\u660e\u78ba\u306b\u5206\u96e2\u3055\u308c\u3066\u3044\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u793e\u5185\u691c\u8a3c\u306e\u305f\u3081\u306b\u3001\u6280\u8853\u7684\u306a\u30ea\u30af\u30a8\u30b9\u30c8\u306b\u5fdc\u3058\u3066\u5e02\u8ca9\u30b5\u30f3\u30d7\u30eb\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><br>\n    Q2\uff1a\u5316\u7ca7\u54c1\u6eb6\u5a92\u306b\u304a\u3051\u308b\u30c8\u30bf\u30ed\u30fc\u30eb\u306e\u6b63\u78ba\u306a\u6eb6\u89e3\u9650\u5ea6\u306f\u4f55\u3067\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a\u30c8\u30bf\u30ed\u30fc\u30eb\u306f\u30a8\u30bf\u30ce\u30fc\u30eb\uff08&gt;10%\uff09\u3001\u30d7\u30ed\u30d4\u30ec\u30f3\u30b0\u30ea\u30b3\u30fc\u30eb\u3001\u304a\u3088\u3073\u30b9\u30af\u30ef\u30e9\u30f3\u306e\u3088\u3046\u306a\u30ad\u30e3\u30ea\u30a2\u30aa\u30a4\u30eb\u306b\u9ad8\u5ea6\u306b\u6eb6\u89e3\u3057\u307e\u3059\u3002\u6c34\u306b\u306f0%\u6eb6\u89e3\u3057\u307e\u3059\u3002<\/strong><br>\n    Q3\uff1a\u6c34\u6027\u4e73\u6db2\u306b\u304a\u3051\u308b\u30d0\u30af\u30c1\u30aa\u30fc\u30eb\u306e\u9178\u5316\u3092\u9632\u3050\u306b\u306f\u3069\u3046\u3059\u308c\u3070\u3088\u3044\u3067\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1apH\u3092<\/strong><br>\n    \u306e\u9593\u306b\u4fdd\u3063\u3066\u304f\u3060\u3055\u3044\u3002\u30ad\u30ec\u30fc\u30c8\u5264\uff080.05% EDTA\u4e8c\u30ca\u30c8\u30ea\u30a6\u30e0\uff09\u3068\u8102\u6eb6\u6027\u6297\u9178\u5316\u5264\u3092\u8ffd\u52a0\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u30a8\u30a2\u30ec\u30b9\u3001UV\u30ab\u30c3\u30c8\u5bb9\u5668\u306b\u30d1\u30c3\u30b1\u30fc\u30b8\u3057\u3066\u304f\u3060\u3055\u3044\u3002 <span style=\"color: #c53030; font-weight: bold;\">\u306e\u9593\u306b\u7dad\u6301\u3057\u3066\u304f\u3060\u3055\u3044\u3002pH\u3092\u9ad8\u304f\u3059\u308b\u3068\u3001\u8910\u5909\u52b9\u679c\u304c\u52a0\u901f\u3057\u307e\u3059\u3002<\/span>Q4\uff1a90%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u30d0\u30eb\u30af\u5e02\u5834\u4fa1\u683c\u52d5\u5411\u306f\u3069\u3046\u3067\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a\u4fa1\u683c\u306f\u3001\u539f\u6599\u3067\u3042\u308b\u30ea\u30b3\u30ea\u30b9\u6839\u306e\u53ce\u91cf\u3068\u8d85\u81e8\u754c\u6d41\u4f53\u62bd\u51fa\uff08SFE\uff09\u306e\u30b3\u30b9\u30c8\u306b\u5927\u304d\u304f\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u9ad8\u7d14\u5ea6\u30b0\u30ec\u30fc\u30c9\u306f\u5f15\u304d\u7d9a\u304d\u30d7\u30ec\u30df\u30a2\u30e0\u3067\u3059\u3002\u30d6\u30ed\u30fc\u30ab\u30fc\u3092\u4ecb\u3055\u305a\u306b\u4e00\u6b21\u88fd\u9020\u696d\u8005\u304b\u3089\u76f4\u63a5\u8abf\u9054\u3059\u308b\u3053\u3068\u3067\u3001\u5951\u7d04\u4fa1\u683c\u304c\u5b89\u5b9a\u3057\u307e\u3059\u3002<\/strong><br>\n    Q5\uff1a\u690d\u7269\u7531\u6765\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u5264\u306fEU REACH\u306b\u6e96\u62e0\u3057\u3066\u3044\u307e\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u3084\u30c8\u30bf\u30ed\u30fc\u30eb\u306e\u3088\u3046\u306a\u9ad8\u7d14\u5ea6\u62bd\u51fa\u7269\u306f\u3001\u88fd\u9020\u696d\u8005\u306b\u3088\u3063\u3066\u9069\u5207\u306b\u767b\u9332\u3055\u308c\u3066\u3044\u308c\u3070\u3001REACH\u898f\u5236\u306b\u6e96\u62e0\u3057\u3066\u3044\u307e\u3059\u3002\u51e6\u65b9\u524d\u306b\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u304b\u3089\u898f\u5236\u30c9\u30b7\u30a8\u3092\u8981\u6c42\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong><br>\n    Q6\uff1a40%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306890%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u63a8\u5968\u4f7f\u7528\u91cf\u306f\u3069\u306e\u304f\u3089\u3044\u3067\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a40%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u5834\u5408\u3001\u901a\u5e38\u306e\u7528\u9014\u306f<\/strong><br>\n    \u3067\u3059\u300290%\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u5834\u5408\u3001\u4f7f\u7528\u91cf\u306f <span style=\"color: #2b6cb0; font-weight: bold;\">0.05%\uff5e0.2%<\/span>\u306b\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u76ee\u6a19\u3068\u3059\u308b\u6709\u52b9\u6027\u3068\u30b3\u30b9\u30c8\u5236\u7d04\u306b\u57fa\u3065\u3044\u3066\u3001\u6709\u52b9\u6210\u5206\u306e\u30da\u30a4\u30ed\u30fc\u30c9\u3092\u8a08\u7b97\u3057\u3066\u304f\u3060\u3055\u3044\u3002 <span style=\"color: #2b6cb0; font-weight: bold;\">01%\u301c0.05%<\/span>Q7\uff1a\u56fa\u5f62\u690d\u7269\u7531\u6765\u6709\u52b9\u6210\u5206\u306b\u6700\u9069\u306a\u6eb6\u89e3\u6027\u3092\u63d0\u4f9b\u3059\u308b\u30ad\u30e3\u30ea\u30a2\u30aa\u30a4\u30eb\u306f\u4f55\u3067\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">A\uff1a\u30aa\u30af\u30bf\u30c9\u30c7\u30ab\u30ce\u30fc\u30eb\u3068\u30ab\u30d7\u30ea\u30eb\/\u30ab\u30d7\u30ea\u30f3\u9178\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306f\u512a\u308c\u305f\u6eb6\u89e3\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u63d0\u4f9b\u3057\u3001\u30c8\u30bf\u30ed\u30fc\u30eb\u306e\u3088\u3046\u306a\u56fa\u5f62\u6709\u52b9\u6210\u5206\u3092\u6eb6\u89e3\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u9ad8\u6e29\u3067\u3082\u5b89\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><br>\n    Q8\uff1aLicochalcone A\u3068\u30b5\u30ea\u30c1\u30eb\u9178\u306f\u30cb\u30ad\u30d3\u7528\u88fd\u5264\u3067\u5171\u5b58\u3067\u304d\u307e\u3059\u304b\uff1f<\/p>\n\n    <p><strong style=\"color: #2b6cb0;\">Q8: Licochalcone A\u3068\u30b5\u30ea\u30c1\u30eb\u9178\u306f\u30cb\u30ad\u30d3\u7528\u88fd\u5264\u306b\u5171\u5b58\u3067\u304d\u307e\u3059\u304b\uff1f<\/strong><br>\n    \u306f\u3044\u3002\u30ea\u30b3\u30ab\u30eb\u30b3\u30f3A\u306fBHA\u306b\u3088\u308b\u523a\u6fc0\u3092\u8efd\u6e1b\u3057\u307e\u3059\u3002\u6700\u7d42\u7684\u306apH\u304c4.0\uff5e4.5\u7a0b\u5ea6\u306b\u306a\u308b\u3088\u3046\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u30ea\u30b3\u30ab\u30eb\u30b3\u30f3A\u306f\u3001\u9ad8\u5ea6\u306b\u9178\u6027\u306a\u6c34\u6027\u74b0\u5883\u4e0b\u3067\u5909\u8272\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u5b89\u5b9a\u6027\u3092\u6ce8\u610f\u6df1\u304f\u76e3\u8996\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n  <\/div>\n\n  <div style=\"border-top: 1px solid #e2e8f0; margin-top: 40px; padding-top: 20px;\">\n    <h2 id=\"references\" style=\"color: #4a5568; font-size: 18px;\">\u79d1\u5b66\u7684\u53c2\u8003\u6587\u732e<\/h2>\n    <ol style=\"color: #718096; font-size: 14px; padding-left: 20px;\">\n      <li style=\"margin-bottom: 5px;\"><em>\u6a2a\u7530 \u9686\u3089 (1998). \u7518\u8349\u62bd\u51fa\u7269\u7531\u6765\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306e\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u304a\u3088\u3073\u708e\u75c7\u306b\u5bfe\u3059\u308b\u6291\u5236\u52b9\u679c. Pigment Cell Research, 11(6), 355-361.<\/em><\/li>\n      <li style=\"margin-bottom: 5px;\"><em>Micol, V. \u3089 (2001). \u30b8\u30c6\u30eb\u30da\u30f3 \u30c8\u30c8\u30e9\u30ed\u30fc\u30eb\u306e\u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc\u306b\u5bfe\u3059\u308b\u6297\u83cc\u6d3b\u6027. FEBS Letters, 504(2), 154-158.<\/em><\/li>\n      <li style=\"margin-bottom: 5px;\"><em>Evans, C. E. \u3089 (2012). \u30c8\u30c8\u30e9\u30ed\u30fc\u30eb\u306e\u6297\u83cc\u52b9\u679c\u3068\u305d\u306e\u5316\u7ca7\u54c1\u88fd\u5264\u3078\u306e\u5fdc\u7528. International Journal of Cosmetic Science.<\/em><\/li>\n      <li style=\"margin-bottom: 5px;\"><em>Chaudhuri, R. K., &amp; Bojanowski, K. (2014). \u30d0\u30af\u30c1\u30aa\u30fc\u30eb\uff1a\u907a\u4f1d\u5b50\u767a\u73fe\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u306b\u3088\u308a\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u30ec\u30c1\u30ce\u30fc\u30eb\u69d8\u6a5f\u80fd\u6027\u5316\u5408\u7269\u3067\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u52b9\u679c\u304c\u81e8\u5e8a\u7684\u306b\u8a3c\u660e\u3055\u308c\u3066\u3044\u308b. International Journal of Cosmetic Science, 36(3), 221-230.<\/em><\/li>\n    <\/ol>\n  <\/div>\n\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u76ee\u6b21 1. \u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\uff1a\u30c1\u30ed\u30b7\u30ca\u30fc\u30bcIC50\u3068\u8272\u306e\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5 2. \u30c8\u30bf\u30ed\u30fc\u30eb\uff1aMIC\u306e\u73fe\u5b9f\u3068\u7d50\u6676\u5316\u30ea\u30b9\u30af 3. \u30d0\u30af\u30c1\u30aa\u30fc\u30eb\uff1a\u9178\u5316\u611f\u53d7\u6027\u3068pH\u9650\u754c\u2026<\/p>","protected":false},"author":1,"featured_media":14369,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-15171","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Formulation Realities of Plant-Based Skincare Actives: Hard Data on Glabridin, Totarol, and Bakuchiol - Shaanxi Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.totarolchina.com\/ja\/formulation-realities-of-plant-based-skincare-actives-hard-data-on-glabridin-totarol-and-bakuchiol\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Formulation Realities of Plant-Based Skincare Actives: Hard Data on Glabridin, Totarol, and Bakuchiol\" \/>\n<meta property=\"og:description\" content=\"Table of Contents 1. 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