{"id":15128,"date":"2026-07-29T07:23:11","date_gmt":"2026-07-29T07:23:11","guid":{"rendered":"https:\/\/www.totarolchina.com\/?p=15128"},"modified":"2026-07-29T07:23:12","modified_gmt":"2026-07-29T07:23:12","slug":"glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability","status":"publish","type":"post","link":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/","title":{"rendered":"\ud65c\uc131 \uc2a4\ud0a8\ucf00\uc5b4\uc5d0\uc11c\uc758 \uae00\ub77c\ube0c\ub9ac\ub518 \ud30c\uc6b0\ub354: IC50, \uc6a9\ud574\ub3c4 \ubc0f \uc81c\ud615 \uc548\uc815\uc131 \ub370\uc774\ud130 \uc218\uc815"},"content":{"rendered":"
\n

\n \uc81c\ud615 \uac1c\ubc1c\uc790\ub4e4\uc740 \uc2dd\ubb3c \uae30\ubc18 \ud65c\uc131 \uc131\ubd84\uc5d0\uc11c \uc790\uc8fc \ub09c\uad00\uc5d0 \ubd80\ub52a\ud799\ub2c8\ub2e4. \uc2e4\ud5d8\uc2e4\uc5d0\uc11c\ub294 \uc720\ud654\uc561\uc774 \uae68\ub057\ud574 \ubcf4\uc785\ub2c8\ub2e4. 3\uac1c\uc6d4 \ud6c4? \ud06c\ub9bc\uc774 \uac08\uc0c9\uc73c\ub85c \ubcc0\ud569\ub2c8\ub2e4. \ud65c\uc131 \uc131\ubd84\uc774 \ubd84\ud574\ub429\ub2c8\ub2e4. \uc784\uc0c1 \ud6a8\ub2a5\uc774 \uae09\uac10\ud569\ub2c8\ub2e4. \uc65c \uc774\ub7f0 \uc77c\uc774 \ubc1c\uc0dd\ud560\uae4c\uc694? \uc6b0\ub9ac\ub294 \uc885\uc885 \uc131\ubd84\uc758 \ubb3c\ub9ac\ud654\ud559\uc801 \ud2b9\uc131\uc744 \uac04\uacfc\ud569\ub2c8\ub2e4.\n <\/p>\n\n

\n \uac10\ucd08 \ubfcc\ub9ac \ucd94\ucd9c\ubb3c\uc740 \uc5c4\uaca9\ud55c \ubc30\ud569 \uaddc\uce59\uc744 \uc694\uad6c\ud569\ub2c8\ub2e4. \uace0\uc21c\ub3c4 \uae00\ub77c\ube0c\ub9ac\ub518 \ud30c\uc6b0\ub354<\/a> \ub85c \uc791\uc5c5\ud558\ub294 \uac83\uc740 \uc5c4\uaca9\ud55c \uc628\ub3c4 \uc81c\uc5b4\uc640 \ud2b9\uc815 \uc6a9\ub9e4 \uce90\ub9ac\uc5b4\ub97c \uad00\ub9ac\ud558\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc2e4\uc81c \uc2e4\ud5d8\uc2e4 \ub370\uc774\ud130\ub97c \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4. \uc774 \ubd84\uc790\ub97c \ud0f1\ud06c \uc548\uc5d0\uc11c \uadf8\ub300\ub85c \uc720\uc9c0\ud558\uace0 \ud65c\uc131\uc744 \uc720\uc9c0\ud558\ub294 \ubc29\ubc95\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.\n <\/p>\n\n

\n IC50 \ud574\ub3c5: \uc9c4\uc815\ud55c \uba5c\ub77c\ub2cc \ucc28\ub2e8 \ub2a5\ub825\n <\/h2>\n\n

\n \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c\ub294 \uba5c\ub77c\ub2cc \uc0dd\uc131\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 IC50 \uac12(\ubc18\uc218 \ucd5c\ub300 \uc5b5\uc81c \ub18d\ub3c4)\uc744 \uc0ac\uc6a9\ud558\uc5ec \uc131\ubd84\uc774 \uc774 \ud6a8\uc18c\ub97c \uc5bc\ub9c8\ub098 \uc798 \ucc28\ub2e8\ud558\ub294\uc9c0 \uce21\uc815\ud569\ub2c8\ub2e4. \ub0ae\uc740 \uc218\uce58\uac00 \ub354 \uac15\ub825\ud55c \ucc28\ub2e8 \ub2a5\ub825\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ub9c8\ucf00\ud305 \uc790\ub8cc\ub294 \uc774\ub7ec\ud55c \uc218\uce58\ub97c \ub04a\uc784\uc5c6\uc774 \ubd80\ud480\ub9bd\ub2c8\ub2e4. \ud45c\uc900 \uc2dc\ud5d8\uad00 \ub0b4 \ubc84\uc12f \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \ubd84\uc11d\uc5d0 \uc758\uc874\ud569\uc2dc\ub2e4.\n <\/p>\n\n

\n \uc21c\uc218 \uae00\ub77c\ube0c\ub9ac\ub518<\/a> \uc804\ud1b5\uc801\uc778 \uc131\ubd84\ubcf4\ub2e4 \ud6e8\uc52c \ub6f0\uc5b4\ub0a9\ub2c8\ub2e4. \uc81c\ud615\uc5d0 \uacfc\ub3c4\ud558\uac8c \ud22c\uc785\ud560 \ud544\uc694\uac00 \uc5c6\uc2b5\ub2c8\ub2e4. \ub300\ub7c9 \ud22c\uc785 \ube44\uc728\uc740 \uc608\uc0b0\uc744 \ub0ad\ube44\ud558\uace0 \ud53c\ubd80 \uc790\uadf9\uc744 \uc720\ubc1c\ud560 \ubfd0\uc785\ub2c8\ub2e4. \uae30\ub2a5\uc801 \uc6a9\ub7c9\uc740 05%\uc640 0.2% \uc0ac\uc774\uc785\ub2c8\ub2e4.<\/span>.\n <\/p>\n\n \n \n \n \n \n \n \n
\ud65c\uc131 \ud654\ud569\ubb3c<\/th>\n IC50 \uac12 (\u00b5g\/mL)<\/th>\n \uc0c1\ub300 \uac15\ub3c4<\/th>\n \uc0b0\ud654 \uc704\ud5d8<\/th>\n <\/tr>\n <\/thead>\n
\uae00\ub77c\ube0c\ub9ac\ub518 (90% \ub4f1\uae09)<\/td>\n 45 \u2013 1.5<\/td>\n \uadf9\uc2ec\ud568 (\uae30\uc900\uce58 10\ubc30 \uc774\uc0c1)<\/td>\n \ubcf4\ud1b5<\/td>\n <\/tr>\n
\ucf54\uc9c1\uc0b0<\/td>\n 0 \u2013 14.0<\/td>\n \uae30\uc900\uc120 (1x)<\/td>\n \ub192\uc74c<\/td>\n <\/tr>\n
\uc54c\ud30c-\uc54c\ubd80\ud2f4<\/td>\n 0 \u2013 65.0<\/td>\n \ub0ae\uc74c<\/td>\n \ub0ae\uc74c<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n

\n COA \ud310\ub3c5: \ud63c\ud569\ubb3c \ub300 \uc21c\uc218 \ubd84\uc790\n <\/h2>\n\n

\n 40% \ucd94\ucd9c\ubb3c\uc5d0 \ub300\ud574 \uacf5\uae09\uc5c5\uccb4\uac00 \uba85\ud655\ud55c \ub179\ub294\uc810\uc744 \uc9c0\uc815\ud569\ub2c8\uae4c? \uacfc\ud559\uc801\uc73c\ub85c \ubd88\uac00\ub2a5\ud569\ub2c8\ub2e4. 40% \ub4f1\uae09\uc740 \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc\uc758 \uc2dd\ubb3c\uc131 \ud63c\ud569\ubb3c\uc785\ub2c8\ub2e4. \ud63c\ud569\ubb3c\uc740 \ub113\uc740 \ubc94\uc704\uc5d0 \uac78\uccd0 \ubd80\ub4dc\ub7ec\uc6cc\uc9d1\ub2c8\ub2e4. \uace0\uc21c\ub3c4 \ubd84\uc790(90% \ub610\ub294 98% \ub4f1\uae09\uacfc \uac19\uc740)\ub9cc\uc774 \uc9c4\uc815\ud55c \uba85\ud655\ud55c \ub179\ub294\uc810\uc744 \uac00\uc9d1\ub2c8\ub2e4. \n <\/p>\n\n

\n \ub178\ub780\uc0c9 \uc0c9\uc870\uac00 \ud5c8\uc6a9\ub418\ub294 \uc5b4\ub450\uc6b4 \uc138\ub7fc \ub610\ub294 \ubc14\ub514 \ub85c\uc158\uc5d0\ub294 40% \ub4f1\uae09\uc744 \uc120\ud0dd\ud558\uc2ed\uc2dc\uc624. \ud22c\uba85\ud55c \ud1a0\ub108 \ub610\ub294 \ud504\ub9ac\ubbf8\uc5c4 \ud770\uc0c9 \uc720\ud654\uc561\uc744 \uc81c\ud615\ud558\ub294 \uacbd\uc6b0, 90% \ub4f1\uae09\uc740 \uc5c4\uaca9\ud788 \ud544\uc218\uc785\ub2c8\ub2e4.<\/span> \ubbf8\uc801 \ubcc0\ud654\ub97c \ubc29\uc9c0\ud558\uae30 \uc704\ud574.\n <\/p>\n\n \n \n \n \n \n \n \n
\uc0ac\uc591 \ub9e4\uac1c\ubcc0\uc218<\/th>\n 40% \ud45c\uc900 \ub4f1\uae09<\/th>\n 90% \uc815\uc81c \ub4f1\uae09<\/th>\n <\/tr>\n <\/thead>\n
\uc678\uad00<\/td>\n \uac08\uc0c9\uc5d0\uc11c \ud669\uac08\uc0c9<\/td>\n \uc5f0\ud55c \ub178\ub780\uc0c9\uc5d0\uc11c \ubbf8\uc0c9<\/td>\n <\/tr>\n
\ub179\ub294\uc810<\/td>\n \ud574\ub2f9 \uc5c6\uc74c (\ubcf5\uc7a1\ud55c \ud63c\ud569\ubb3c)<\/td>\n 156\u00b0C \u2013 158\u00b0C<\/td>\n <\/tr>\n
\uc218\uc6a9\ud574\ub3c4<\/td>\n \ubd88\uc6a9\uc131<\/td>\n \ubd88\uc6a9\uc131<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n

\n \uc6a9\ud574\ub3c4 \ud568\uc815: \uc81c\ud615\uc774 \uc2e4\ud328\ud558\ub294 \uc774\uc720\n <\/h2>\n\n

\n \uc774 \uc131\ubd84\uc740 \ubb3c\uc744 \uc2eb\uc5b4\ud569\ub2c8\ub2e4. \uac15\ud55c \uce5c\uc720\uc131\uc785\ub2c8\ub2e4. \uc218\uc131 \uc0c1\uc5d0 \uc9c1\uc811 \ubd93\ub294 \uac83\uc740 \uc2e4\ud328\ub97c \ubcf4\uc7a5\ud569\ub2c8\ub2e4. \ub5a0\ub2e4\ub2c8\uace0, \ubb49\uce58\uace0, \uacb0\uad6d \uce68\uc804\ub420 \uac83\uc785\ub2c8\ub2e4. \ud718\ubc1c\uc131 \uc6a9\ub9e4\uc5d0\uc11c \uacf5\uaca9\uc801\uc73c\ub85c \uac00\uc5f4\ud558\ub294 \uac83\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\ub85c \ub098\uc069\ub2c8\ub2e4. \uc6a9\ub9e4\uac00 \uc99d\ubc1c\ud558\uba74 \ud65c\uc131 \uc131\ubd84\uc774 \uac08 \uacf3\uc774 \uc5c6\uc5b4\uc9d1\ub2c8\ub2e4. \uce68\uc804\ub418\uc5b4 \uacb0\uc815\ud654\ub429\ub2c8\ub2e4.\n <\/p>\n\n

\n

\uc62c\ubc14\ub978 \ubc30\ud569 \ud504\ub85c\ud1a0\ucf5c<\/h3>\n
    \n
  • \uce90\ub9ac\uc5b4 \uc120\ud0dd:<\/strong> \uc5d0\ud0c4\uc62c\uc744 \ud53c\ud558\uc2ed\uc2dc\uc624. \ubd80\ud2f8\ub80c \uae00\ub9ac\ucf5c (1,3-BG), \ud504\ub85c\ud544\ub80c \uae00\ub9ac\ucf5c \ub610\ub294 PEG-400\uc744 \uc0ac\uc6a9\ud558\uc2ed\uc2dc\uc624.<\/li>\n
  • \uc5f4 \uc81c\uc5b4:<\/strong> \uc6a9\ub9e4\ub97c 40\u00b0C \u2013 50\u00b0C<\/span>\ub85c \ub530\ub73b\ud558\uac8c \ud558\uc2ed\uc2dc\uc624. \uc644\uc804\ud788 \ud22c\uba85\ud574\uc9c8 \ub54c\uae4c\uc9c0 \uc800\uc5b4\uc90d\ub2c8\ub2e4. \ub192\uc740 \uc5f4\uc740 \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc \uc0b0\ud654\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.<\/li>\n
  • \ud1b5\ud569 \ub2e8\uacc4:<\/strong> \ub9c8\uc9c0\ub9c9 \ub0c9\uac01 \ub2e8\uacc4(40\u00b0C \ubbf8\ub9cc) \uc911\uc5d0 \ud504\ub9ac\ubbf9\uc2a4\ub97c \ub3c4\uc785\ud558\uc2ed\uc2dc\uc624.<\/li>\n
  • pH \uc644\ucda9:<\/strong> \ucd5c\uc885 \uc720\ud654\uc561 pH\ub97c 4.5\uc5d0\uc11c 6.5 \uc0ac\uc774\ub85c \uace0\uc815\ud558\uc2ed\uc2dc\uc624. \uc54c\uce7c\ub9ac\uc131 \ud658\uacbd\uc740 \ubd84\uc790 \uad6c\uc870\ub97c \ud30c\uad34\ud569\ub2c8\ub2e4.<\/li>\n <\/ul>\n <\/div>\n\n

    \n \uacf5\uc7a5 \uc0ac\ub840 \uc5f0\uad6c: \ubd84\ud64d\ube5b \uac08\uc0c9 \ub85c\uc158\n <\/h2>\n\n

    \n \ucd5c\uadfc \ud55c \uacc4\uc57d \uc81c\uc870\uc5c5\uccb4\uc5d0\uc11c 500kg \ubc30\uce58 \ube0c\ub77c\uc774\ud2b8\ub2dd \ub85c\uc158\uc774 4\uc8fc\ucc28\uc5d0 \uc2e4\ud328\ud558\ub294 \uac83\uc744 \ubaa9\uaca9\ud588\uc2b5\ub2c8\ub2e4. \uc561\uccb4\uac00 \ubd84\ud64d\ube5b \uac08\uc0c9\uc73c\ub85c \ubcc0\ud588\uc2b5\ub2c8\ub2e4. \uacb0\uc815\uc774 \ud38c\ud504 \uba54\ucee4\ub2c8\uc998\uc744 \ub9c9\uc558\uc2b5\ub2c8\ub2e4. \uc989\uc2dc SOP\ub97c \uac10\uc0ac\ud588\uc2b5\ub2c8\ub2e4.\n <\/p>\n \n

    \n \uadf8\ub4e4\uc740 \ub450 \uac00\uc9c0 \uce58\uba85\uc801\uc778 \uc2e4\uc218\ub97c \uc800\uc9c8\ub800\uc2b5\ub2c8\ub2e4. \uccab\uc9f8, 60\u00b0C\uc5d0\uc11c \ucd5c\uc18c\ud55c\uc758 \uc5d0\ud0c4\uc62c\uc5d0 \ud65c\uc131 \uc131\ubd84\uc744 \ub179\uc600\uc2b5\ub2c8\ub2e4. \ub458\uc9f8, \uc21c\uc218 \uc544\uc2a4\ucf54\ub974\ube0c\uc0b0\uc73c\ub85c \ud3ec\ud654\ub41c \uace0\uc0b0\uc131 \ubca0\uc774\uc2a4(pH 3.5)\uc5d0 \ubd80\uc5c8\uc2b5\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \uc2e0\uc18d\ud55c \ud574\uacb0\ucc45\uc744 \uc124\uacc4\ud588\uc2b5\ub2c8\ub2e4. \uc5d0\ud0c4\uc62c\uc744 PEG-400\uc73c\ub85c \uad50\uccb4\ud588\uc2b5\ub2c8\ub2e4. \uc6a9\ud574 \uc628\ub3c4\ub97c 45\u00b0C\ub85c \ub0ae\ucdc4\uc2b5\ub2c8\ub2e4. \ub9c8\uc9c0\ub9c9\uc73c\ub85c \uc2dc\uc2a4\ud15c\uc744 pH 5.5\ub85c \uc644\ucda9\ud558\uace0 \ud718\ubc1c\uc131 \uc544\uc2a4\ucf54\ub974\ube0c\uc0b0\uc744 \uc544\uc2a4\ucf54\ube4c \uae00\ub8e8\ucf54\uc0ac\uc774\ub4dc\ub85c \uad50\uccb4\ud588\uc2b5\ub2c8\ub2e4. \ub2e4\uc74c \ud30c\uc77c\ub7ff \ubc30\uce58\uc5d0\uc11c 45\u00b0C\uc5d0\uc11c 12\uc8fc\uac04\uc758 \uac00\uc18d \ud14c\uc2a4\ud2b8\ub97c \ud1b5\uacfc\ud588\uc73c\uba70 \ubd84\ud574\ub294 \uc804\ud600 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4.\n <\/p>\n\n

    \n \uc0b0\uc5c5 \uaddc\uc815 \uc900\uc218 \ubc0f \uc81c\ud615 \ubbf8\ub798\n <\/h2>\n\n

    \n \uaddc\uc81c \ub2f9\uad6d\uc740 \ud569\uc131 \ud45c\ubc31\uc81c\ub97c \uc9c8\uc2dd\uc2dc\ud0a4\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud558\uc774\ub4dc\ub85c\ud034\ub17c \uae08\uc9c0\ub294 \uc720\ub7fd, \uc601\uad6d \ubc0f \uc8fc\uc694 \uc544\uc2dc\uc544 \uc2dc\uc7a5 \uc804\ubc18\uc5d0 \uac78\uccd0 \uc5c4\uaca9\ud558\uac8c \uc2dc\ud589\ub429\ub2c8\ub2e4. \ube0c\ub79c\ub4dc\ub294 \uac15\ub825\ud55c \uc2dd\ubb3c\uc131 \ub300\uc548\uc744 \uc694\uad6c\ud569\ub2c8\ub2e4.\n <\/p>\n\n

    \n \uc2dd\ubb3c \uc720\ub798 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c\uc81c\ub294 \uc774 \ubd84\uc57c\ub97c \uc9c0\ubc30\ud569\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \uc774\uc911 \uae30\ub2a5\uc744 \uc81c\uacf5\ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uba5c\ub77c\ub2cc \ud569\uc131\uc744 \uba48\ucda5\ub2c8\ub2e4. \ub610\ud55c COX-2 \ubc1c\ud604\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uc5ec UVB \uc720\ubc1c \uc5fc\uc99d\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uba5c\ub77c\ub2cc \uc138\ud3ec\uac00 \ubc18\uc751\ud558\ub3c4\ub85d \uac15\uc694\ud558\uae30 \uc804\uc5d0 \uc0dd\ubb3c\ud559\uc801 \ud2b8\ub9ac\uac70\ub97c \ucc28\ub2e8\ud569\ub2c8\ub2e4. \uacac\uace0\ud55c \ud654\ud559\uc744 \uae30\ubc18\uc73c\ub85c \uc100\uc2dc\ub97c \uad6c\ucd95\ud558\uc2ed\uc2dc\uc624. \uc6a9\ud574\ub3c4 \uacbd\uacc4\ub97c \uc874\uc911\ud558\uc2ed\uc2dc\uc624. \uc784\uc0c1 \ud6a8\ub2a5\uc740 \uc790\uc5f0\uc2a4\ub7fd\uac8c \ub530\ub77c\uc62c \uac83\uc785\ub2c8\ub2e4.\n <\/p>\n\n

    \n\n

    \n \uacf5\uac1c \uacfc\ud559 \ucc38\uace0 \ubb38\ud5cc \ubc0f \ubb38\ud5cc\n <\/h3>\n
      \n
    • Yokota, T., et al. (1998). \u201c\uac10\ucd08 \ucd94\ucd9c\ubb3c\uc5d0\uc11c \ucd94\ucd9c\ud55c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uba5c\ub77c\ub178\uc81c\ub124\uc2dc\uc2a4 \ubc0f \uc5fc\uc99d \uc5b5\uc81c \ud6a8\uacfc.\u201d \uc0c9\uc18c\uc138\ud3ec \uc5f0\uad6c<\/i>, 11(6), 355-361.<\/li>\n
    • Nerya, O. \ub4f1 (2003). \"Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots.\" \ub18d\uc5c5 \ubc0f \uc2dd\ud488 \ud654\ud559 \uc800\ub110<\/i>, 51(5), 1201-1207.<\/li>\n
    • Simmler, C. \ub4f1 (2013). \"Licorice roots: A versatile botanical dietary supplement.\" \uc57d\ucd08\ud559<\/i>, 90, 106-121.<\/li>\n
    • D\u2019Mello, S. A. \ub4f1 (2016). \"Signaling Pathways in Melanogenesis.\" \uad6d\uc81c \ubd84\uc790 \uacfc\ud559 \uc800\ub110<\/i>, 17(7), 1144.<\/li>\n <\/ul>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

      \uc81c\ud615 \uac1c\ubc1c\uc790\ub4e4\uc740 \uc2dd\ubb3c \uc720\ub798 \ud65c\uc131 \uc131\ubd84\uc73c\ub85c \uc778\ud574 \uc790\uc8fc \ub09c\uad00\uc5d0 \ubd80\ub52a\ud799\ub2c8\ub2e4. \uc2e4\ud5d8\uc2e4\uc5d0\uc11c\ub294 \uc720\ud654\uc561\uc774 \uc644\ubcbd\ud574 \ubcf4\uc785\ub2c8\ub2e4. 3\uac1c\uc6d4 \ud6c4\uc5d0\ub294\uc694? \ud06c\ub9bc\uc774 \uac08\ubcc0\ud569\ub2c8\ub2e4. \ud65c\uc131 \uc131\ubd84\uc774 \ubd84\ud574\ub418\ub294 \uac83\uc785\ub2c8\ub2e4\u2026.<\/p>","protected":false},"author":1,"featured_media":14383,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-15128","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new"],"yoast_head":"\nGlabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability - Shaanxi Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability\" \/>\n<meta property=\"og:description\" content=\"Formulators frequently hit a wall with plant-based actives. The emulsion looks pristine in the lab. Three months later? The cream turns brown. The active degrades....\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\" \/>\n<meta property=\"og:site_name\" content=\"Shaanxi Huatai Bio\" \/>\n<meta property=\"article:published_time\" content=\"2026-07-29T07:23:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-29T07:23:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1810\" \/>\n\t<meta property=\"og:image:height\" content=\"2560\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"liuhana978@gmail.com\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\uae00\uc4f4\uc774\" \/>\n\t<meta name=\"twitter:data1\" content=\"liuhana978@gmail.com\" \/>\n\t<meta name=\"twitter:label2\" content=\"\uc608\uc0c1 \ub418\ub294 \ud310\ub3c5 \uc2dc\uac04\" \/>\n\t<meta name=\"twitter:data2\" content=\"4\ubd84\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\"},\"author\":{\"name\":\"liuhana978@gmail.com\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed\"},\"headline\":\"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability\",\"datePublished\":\"2026-07-29T07:23:11+00:00\",\"dateModified\":\"2026-07-29T07:23:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\"},\"wordCount\":710,\"publisher\":{\"@id\":\"https:\/\/www.totarolchina.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg\",\"articleSection\":[\"New\"],\"inLanguage\":\"ko-KR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\",\"url\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\",\"name\":\"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability - Shaanxi Huatai Bio\",\"isPartOf\":{\"@id\":\"https:\/\/www.totarolchina.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg\",\"datePublished\":\"2026-07-29T07:23:11+00:00\",\"dateModified\":\"2026-07-29T07:23:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#breadcrumb\"},\"inLanguage\":\"ko-KR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ko-KR\",\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage\",\"url\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg\",\"contentUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg\",\"width\":1810,\"height\":2560,\"caption\":\"glabridin\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.totarolchina.com\/ko\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.totarolchina.com\/#website\",\"url\":\"https:\/\/www.totarolchina.com\/\",\"name\":\"Shaanxi Huatai Bio\",\"description\":\"Huatai Bio empowers global skincare brands by supplying top-tier cosmetic actives that prioritize safety and performance. Our extensive portfolio, backed by ISO, COSMOS, and HALAL quality standards, provides the essential building blocks for innovative beauty formulations. Explore our range of compliant, high-efficacy ingredients designed to elevate your skincare line.\",\"publisher\":{\"@id\":\"https:\/\/www.totarolchina.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.totarolchina.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ko-KR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.totarolchina.com\/#organization\",\"name\":\"Shaanxi Huatai Bio\",\"url\":\"https:\/\/www.totarolchina.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ko-KR\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp\",\"contentUrl\":\"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp\",\"width\":300,\"height\":184,\"caption\":\"Shaanxi Huatai Bio\"},\"image\":{\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed\",\"name\":\"liuhana978@gmail.com\",\"sameAs\":[\"http:\/\/totarolchina.com\"],\"url\":\"https:\/\/www.totarolchina.com\/ko\/author\/liuhana978gmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability - Shaanxi Huatai Bio","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/","og_locale":"ko_KR","og_type":"article","og_title":"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability","og_description":"Formulators frequently hit a wall with plant-based actives. The emulsion looks pristine in the lab. Three months later? The cream turns brown. The active degrades....","og_url":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/","og_site_name":"Shaanxi Huatai Bio","article_published_time":"2026-07-29T07:23:11+00:00","article_modified_time":"2026-07-29T07:23:12+00:00","og_image":[{"width":1810,"height":2560,"url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg","type":"image\/jpeg"}],"author":"liuhana978@gmail.com","twitter_card":"summary_large_image","twitter_misc":{"\uae00\uc4f4\uc774":"liuhana978@gmail.com","\uc608\uc0c1 \ub418\ub294 \ud310\ub3c5 \uc2dc\uac04":"4\ubd84"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#article","isPartOf":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/"},"author":{"name":"liuhana978@gmail.com","@id":"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed"},"headline":"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability","datePublished":"2026-07-29T07:23:11+00:00","dateModified":"2026-07-29T07:23:12+00:00","mainEntityOfPage":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/"},"wordCount":710,"publisher":{"@id":"https:\/\/www.totarolchina.com\/#organization"},"image":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage"},"thumbnailUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg","articleSection":["New"],"inLanguage":"ko-KR"},{"@type":"WebPage","@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/","url":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/","name":"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability - Shaanxi Huatai Bio","isPartOf":{"@id":"https:\/\/www.totarolchina.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage"},"image":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage"},"thumbnailUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg","datePublished":"2026-07-29T07:23:11+00:00","dateModified":"2026-07-29T07:23:12+00:00","breadcrumb":{"@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#breadcrumb"},"inLanguage":"ko-KR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/"]}]},{"@type":"ImageObject","inLanguage":"ko-KR","@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#primaryimage","url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg","contentUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/05\/high-purity-Glabridin-scaled.jpg","width":1810,"height":2560,"caption":"glabridin"},{"@type":"BreadcrumbList","@id":"https:\/\/www.totarolchina.com\/ko\/glabridin-powder-in-active-skincare-correcting-the-data-on-ic50-solubility-and-formulation-stability\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.totarolchina.com\/ko\/"},{"@type":"ListItem","position":2,"name":"Glabridin Powder in Active Skincare: Correcting the Data on IC50, Solubility, and Formulation Stability"}]},{"@type":"WebSite","@id":"https:\/\/www.totarolchina.com\/#website","url":"https:\/\/www.totarolchina.com\/","name":"Shaanxi Huatai Bio","description":"Huatai Bio empowers global skincare brands by supplying top-tier cosmetic actives that prioritize safety and performance. Our extensive portfolio, backed by ISO, COSMOS, and HALAL quality standards, provides the essential building blocks for innovative beauty formulations. Explore our range of compliant, high-efficacy ingredients designed to elevate your skincare line.","publisher":{"@id":"https:\/\/www.totarolchina.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.totarolchina.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ko-KR"},{"@type":"Organization","@id":"https:\/\/www.totarolchina.com\/#organization","name":"Shaanxi Huatai Bio","url":"https:\/\/www.totarolchina.com\/","logo":{"@type":"ImageObject","inLanguage":"ko-KR","@id":"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp","contentUrl":"https:\/\/www.totarolchina.com\/wp-content\/uploads\/2026\/03\/LOGO-300x184-1.webp","width":300,"height":184,"caption":"Shaanxi Huatai Bio"},"image":{"@id":"https:\/\/www.totarolchina.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.totarolchina.com\/#\/schema\/person\/f527e330ba607dc584aa38354b43e9ed","name":"liuhana978@gmail.com","sameAs":["http:\/\/totarolchina.com"],"url":"https:\/\/www.totarolchina.com\/ko\/author\/liuhana978gmail-com\/"}]}},"_links":{"self":[{"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/posts\/15128","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/comments?post=15128"}],"version-history":[{"count":1,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/posts\/15128\/revisions"}],"predecessor-version":[{"id":15129,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/posts\/15128\/revisions\/15129"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/media\/14383"}],"wp:attachment":[{"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/media?parent=15128"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/categories?post=15128"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.totarolchina.com\/ko\/wp-json\/wp\/v2\/tags?post=15128"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}