Kaempferol

Kaempferol is a potent, naturally occurring flavonoid found in numerous plant sources (e.g., Sophora japonica, tea, broccoli). As an advanced active, it provides superior, multi-targeted benefits, including powerful free radical scavenging, effective anti-inflammatory action by inhibiting key enzymes, and proven efficacy in protecting against UV-induced damage and preserving skin elasticity.

INCI Name

Kaempferol

CAS No.

520-18-3

Source

Natural Flavonoid (e.g., Sophora japonica)

Purity

≥98%

Core Function

Antioxidant, Anti-inflammatory, Anti-aging, Photoprotection, Collagen Protection

1. Product Overview & Market Relevance

Kaempferol belongs to the flavonol class of flavonoids, known for its extensive biological activity. In cosmetics, it is highly valued for its ability to penetrate the skin and interfere with multiple aging and inflammatory pathways. Its strong defensive capabilities against environmental stressors position it as a premium ingredient in anti-aging, sensitive skin, and dedicated anti-pollution product lines.

2. Technical Highlights and Critical Parameters

2.1 Mechanism of Action

  • Free Radical Scavenging: Exhibits extremely high antioxidant power, effectively neutralizing Reactive Oxygen Species (ROS) generated by UV radiation and pollution.

  • Enzyme Inhibition: Directly inhibits inflammatory enzymes (e.g., COX-2) and Matrix Metalloproteinases (MMPs), which are responsible for breaking down collagen and elastin.

  • Photoprotection: Mitigates cellular damage caused by UVA and UVB exposure, helping to reduce erythema and photoaging markers.

  • Collagen Support: By inhibiting MMPs and supporting cellular health, it helps maintain the skin’s structural integrity and elasticity.

2.2 Standard Technical Specifications

ParameterSpecification (High-Purity Grade)
Specification≥98%
AppearanceYellow powder
Recommended Dosage0.1%-1.0%
SolubilityOil soluble (Soluble in ethanol, propylene glycol)
pH Range3.0-6.0 (Optimal stability range)
StorageCool, dark, sealed container (Avoid strong light/heat)

3. Market Positioning and Core Advantages

  • Multi-Pathway Protection: Provides comprehensive anti-aging benefits by targeting both oxidative stress and enzymatic degradation of the dermal matrix.

  • Natural and High Purity: Meets the demand for high-efficacy, plant-derived actives with guaranteed purity (98% minimum).

  • Synergistic Action: Works exceptionally well when combined with traditional sunscreens, boosting their defensive capabilities against free radical damage.

  • Stability in Low pH: Remains highly stable and active in slightly acidic formulations, making it compatible with actives like Vitamin C and AHAs.

4. Formulation Guidelines

  • Integration Phase: Kaempferol is oil soluble. It must be pre-dissolved in an appropriate solvent (e.g., ethanol, propylene glycol, or oil phase) before incorporation into the main formula.

  • Concentration: Recommended usage is typically between 0.1% and 1.0% of the final product.

  • Stability Control: Due to its sensitivity to strong light and high heat, it should be added during the cooling phase (below 40°C). The final product must be packaged opaquely to maintain long-term stability.

  • pH Control: Optimal stability is achieved within the pH range of 3.0 – 6.0. Avoid highly alkaline systems.

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials include:

  • COSMOS (Natural and Organic Cosmetic Standard)

  • ISO 9001 Quality Management System

  • ISO 22000 Food Safety Management System

  • HALAL Certification

  • IQNET (The International Certification Network)

  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

  • Daily Defense Serums: Used for broad-spectrum environmental protection and antioxidant support.

  • Anti-Aging Creams: Formulations targeting firmness, elasticity, and wrinkle reduction.

  • Sun Care & After-Sun: Boosts UV defense and helps soothe post-exposure inflammation.

  • Sensitive Skin Lines: Calming products due to its anti-inflammatory properties.

7. Scientific Evidence Summary

  • Collagenase Inhibition: Studies confirm its ability to directly inhibit the enzymes (MMPs) that degrade collagen and elastin, preserving skin structure.

  • Photoprotective Effects: Research demonstrates that topical application mitigates key markers of UV damage and photoaging in skin cells.

  • Anti-inflammatory Efficacy: Clinical data supports its role in suppressing inflammatory pathways, leading to a visible reduction in redness and irritation.

8. Frequently Asked Questions

Q1: Is Kaempferol suitable for all skin types?

A: Yes. Its primary actions—antioxidant and anti-inflammatory—are beneficial for all skin types, including sensitive and mature skin, which need protection against environmental stress and collagen breakdown.

Q2: How does Kaempferol contribute to anti-aging compared to Vitamin C?

A: While Vitamin C is essential for direct collagen synthesis, Kaempferol focuses on preventing the breakdown of existing collagen and elastin by inhibiting MMPs, offering a crucial defensive strategy that complements the repair function of Vitamin C.

Q3: Does Kaempferol affect the color of the final product?

A: As a yellow powder, Kaempferol may impart a light yellow or yellowish-green hue to the final formula, especially at higher concentrations. This should be factored into the overall product design and packaging.

 

Source our ≥98% Purity Kaempferol for stable, high-efficacy antioxidant defense, collagen protection, and advanced anti-aging formulations.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

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Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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