Urolithin A

Shaanxi Huatai Bio-fine Chemical Co. provides premium cosmetic grade Urolithin A, characterized by its proven mitochondrial-renewing activity and exceptional biological stability. Our unique advantage lies in the high-purity crystalline form of these active ingredients skincare, which ensures targeted delivery to the mitochondria to trigger the clearance of “exhausted” organelles. As a premier active for the “Cellular Longevity” market, our Urolithin A empowers brands to deliver formulations that fundamentally reboot the skin’s energy production centers, reversing the signs of fatigue and aging at a biological level.

1. Product Overview & Key Specifications

• Urolithin A is a natural metabolite produced following the intake of ellagitannins found in fruits like pomegranates.

• It is highly valued in modern skincare for its ability to improve muscle and skin cell function by optimizing mitochondrial health.

2. Technical Highlights & Critical Parameters

• Our Urolithin A is refined to maintain peak bioactivity while ensuring formulation stability.

• Purity: ≥ 98.0%.

• Heavy Metals: < 10 ppm.

• Loss on Drying: ≤ 1.0%.

• Stability: Excellent stability in lipid-based and emulsion systems.

3. Mechanism of Action (MoA)

• Induction of Mitophagy: Activates the recycling of dysfunctional mitochondria, ensuring only healthy, high-energy mitochondria remain in the cell.

• Energy Boosting: By optimizing the mitochondrial pool, it enhances ATP production, providing more energy for cellular repair and synthesis.

• Inflammation Reduction: Decreases the production of reactive oxygen species (ROS) caused by mitochondrial leakage.

4. Core Advantages & Market USPs

• Targeted “Mito-Aging” Solution: Addresses one of the primary drivers of biological aging—mitochondrial dysfunction.

• Enhanced Skin Vitality: Effectively combats the “tired skin” look by improving cellular metabolism and resilience.

• Premium Longevity Active: Positions products within the high-end “Bio-hacking” and “Age-Reversal” market categories.

5. Formulation Guidelines

• Recommended Usage: 0.05% – 0.5%.

• Processing: Lipophilic; should be pre-dissolved in a suitable oil phase or solvent before emulsification.

• pH Range: Best maintained within a pH range of 5.0 – 7.0 for optimal formulation stability.

6. Quality Assurance & Regulatory Confidence

• Our manufacturing facility is ISO 9001/22000 and HALAL certified.

• We strictly adhere to COSMOS approved standards, ensuring our raw materials meet natural and organic cosmetic criteria.

• Every batch of our cosmetic grade Urolithin A is provided with a full technical dossier, including COA, TDS, and MSDS.

7. Recommended Synergistic Combinations

• Urolithin A + Spermidine HCl: For a complete “Autophagy + Mitophagy” cellular cleanup system.

• Urolithin A + Ergothioneine: To provide the ultimate protection for newly regenerated mitochondria.

• Urolithin A + NAD+ Precursors: To maximize the energy production and repair potential of the skin cells.

8. Typical Applications & Success Stories

• This ingredient is a core component in “Cellular Energy Serums,” “Mitochondrial Repair Creams,” and “Advanced Rejuvenation Night Treatments”.

• Brands using our active ingredients skincare have successfully launched “Biological Energy” lines that show measurable improvements in skin tone and firmness.

9. Scientific Evidence & Literature Support

• Extensive scientific studies highlight Urolithin A as a first-in-class mitophagy activator that improves healthspan and cellular vigor.

• Internal lab data confirms that Urolithin A-enriched formulations significantly improve skin density and reduce fine lines by restoring dermal metabolic activity.

Partner with the High-Purity Urolithin A Supplier of Choice.

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