Functional Sodium Hyaluronate
Specialized Molecular Engineering for Lipophilic Repair, Substantive Adhesion, and Structural Filling
While standard Hyaluronic Acid provides basic moisture, the Functional Sodium Hyaluronate Series from Shaanxi Huatai Bio-fine Chemical Co. represents the frontier of molecular modification. By strategically altering the HA backbone, we have created a suite of high-performance actives tailored for specific delivery challenges: Acetylated HA for deep lipophilic repair, Cationic HA for rinse-off substantivity, and Cross-linked HA for long-lasting structural plumping.
| CAS No. | 9067-32-7 (Basic) / 67905-19-5 (AcHA) / 153304-44-4 (Cationic) |
|---|---|
| Source | Microbial Fermentation (High-Purity Bio-tech) |
| Appearance Color | White to Off-white Powder or Clear Gel/Liquid |
| Key Parameter | Purity >= 95.0% / Specialized Modification Degree |
| Solubility | Water-soluble (Varies by modification; AcHA is amphiphilic) |
1. Key Specifications & Technical Parameters (Commercial Comparison)
| Variant | Key Feature | Market Advantage |
| Acetylated (AcHA) | Amphiphilic (Oil & Water) | Dual-affinity: Deeply repairs the lipid barrier; 2x more moisture retention than standard HA |
| Cationic (Hymagic-ad) | Positively Charged | Anti-rinse: Magnetically binds to hair and skin; ideal for shampoos and cleansers |
| Cross-linked (HA Polymer) | 3D Micro-network | Filler Effect: Resists enzymatic breakdown; provides 24h+ long-lasting plumping |
| Purity (HPLC) | >= 95.0% | Ultra-low protein and heavy metal content for medical-grade safety |
| Skin Feel | Non-sticky / Elegant | Specifically engineered to eliminate the “tackiness” of traditional HA |
| Stability | Enhanced Resistance | Modified structures offer superior resistance to hyaluronidase degradation |
2. Biological Mechanism of Action (MoA)
Our Functional HA series operates through targeted mechanical and biological pathways:
Acetylated Repair (AcHA): The acetyl groups allow the molecule to anchor into the stratum corneum’s lipid bilayer, softening the keratin and repairing the damaged skin barrier while locking in deep moisture.
Cationic Adhesion: Utilizes electrostatic attraction to “stick” to negatively charged skin and hair surfaces. This ensures that even after rinsing, a hydrating protective film remains on the surface.
Cross-linked Scaffolding: Forms a stable, three-dimensional mesh on the skin surface. This “breathable film” acts as a topical filler to instantly smooth fine lines and protect against PM2.5 and environmental pollutants.
3. Formulation & Processing Guidelines
| Parameter | Recommended Standard | Formulation Tip |
| Usage Level | 0.1% to 1.0% (Standard) | Potent effects even at low inclusion rates |
| Intensive Care | Up to 2.0% | Optimized for professional-grade “filler” serums and masks |
| Optimal pH Range | 5.0 to 7.0 | Maintain neutral range to ensure structural stability |
| Processing Temp | Below 60°C | Add to the water phase; avoid high-shear mixing for cross-linked versions |
| Stability Note | Electrolyte Sensitivity | Cationic HA may react with strong anionic surfactants; pre-test compatibility |
4. Market Advantages & Synergies
Specialized Solving: Addresses the “wash-off” problem in cleansers and the “evaporation” problem in dry climates.
Medical-Aesthetic Grade: Provides “needle-free filler” claims for topical products, appealing to consumers seeking non-invasive alternatives.
Texture Customization: Allows formulators to move beyond sticky gels to create silky, luxurious textures in milk, oil, and cream bases.
Recommended Synergistic Blends:
AcHA + Ceramides: The ultimate duo for total lipid barrier reconstruction.
Cationic HA + Panthenol (B5): A high-substantivity repair system for damaged hair and scalp.
Cross-linked HA + Sodium Polyglutamate: Combines a structural moisture film with NMF activation for “all-day” hydration.
5. Quality Assurance & Regulatory Support
Certifications: Manufactured in ISO 9001 and ISO 22000 certified facilities.
Technical Dossier: We provide complete TDS, MSDS, and COA to support global regulatory compliance and performance claims.
Applications: Ideal for “Lipophilic” repair creams, anti-frizz shampoos, 24h “Filling” serums, and hydrating cleansers.
6. Partner with Shaanxi Huatai Bio-fine Chemical Co.
Request a Technical Dossier: Access full molecular modification data and hydration tests.
Apply for a Free Sample: Experience the specific performance of our Functional HA variants.
Customized Quote: Discuss bulk pricing and tailored molecular weight/modification combinations.
English
German
Spanish
French
Japanese
Korean
Portuguese