4-Butylresorcinol 99.0%

Shaanxi Huatai Bio-fine Chemical Co. provides premium cosmetic grade 4-Butylresorcinol characterized by its clinical-level anti-spot potency and high biological affinity. Our unique advantage lies in the material’s ultra-pure crystalline form, ensuring these active ingredients skincare provide a direct and powerful inhibitory effect on the enzymes responsible for hyperpigmentation. Known in the industry as the “Melasma Nemesis,” this active is our signature solution for high-efficacy serums and targeted treatments where traditional brightening ingredients reach their performance limit.

1. Product Overview & Key Specifications

• 4-Butylresorcinol is a functional resorcinol derivative that has become a benchmark for professional skin lightening.

• It is specifically valued for its precision in treating uneven skin tone and localized pigment clusters.

2. Technical Highlights & Critical Parameters

• Our 4-Butylresorcinol is produced to eliminate residual impurities, ensuring stability in final formulations.

• Purity: ≥ 99.0%

• Melting Point: 51.0°C – 54.0°C

• Heavy Metals: < 10 ppm

• Stability: Excellent stability when formulated within the recommended oil phase parameters.

3. Mechanism of Action (MoA)

• Dual Enzyme Inhibition: It acts as a highly effective inhibitor of both Tyrosinase and Peroxidase, the two critical enzymes in the melanogenesis pathway.

• Direct Melanin Suppression: It binds directly to the active site of the enzymes, preventing the conversion of tyrosine into melanin more effectively than Arbutin or Kojic Acid.

4. Core Advantages & Market USPs

• Superior Potency: Exhibits significantly higher inhibitory activity against human tyrosinase compared to 377 and other resorcinol derivatives.

• Targeted Spot Correction: Highly effective for professional-grade products focusing on melasma, sun spots, and age spots.

• Proven Safety Profile: Offers powerful results with a well-documented safety record in high-end cosmetic applications.

5. Formulation Guidelines

• Recommended Usage: 0.1% – 0.5% (effective at very low concentrations).

• Processing: Oil-soluble; should be dissolved in the oil phase or suitable solvents like Propanediol.

• pH Range: Stable within a pH range of 4.5 – 6.0.

6. Quality Assurance & Regulatory Confidence

• Our manufacturing facility is ISO 9001/22000 and HALAL certified.

• We provide a full technical dossier, including COA and MSDS, to ensure our 4-Butylresorcinol meets the strictest global standards for cosmetic grade raw materials.

7. Recommended Synergistic Combinations

• 4-Butylresorcinol + Niacinamide: To block melanin production while simultaneously inhibiting the transfer of pigment to surface cells.

• 4-Butylresorcinol + Tranexamic Acid: A powerful clinical duo for treating inflammation-induced melasma.

• 4-Butylresorcinol + 4-MSK: Combines root inhibition with metabolic clearance for comprehensive brightening.

8. Typical Applications & Success Stories

• This ingredient is a core component in “Intensive Spot Correctors,” “Dermatologist-Grade Brightening Serums,” and “Anti-Melasma Creams.”

• Brands using our high-purity active ingredients skincare have successfully launched products that consistently outperform standard market competitors in visible spot reduction tests.

9. Scientific Evidence & Literature Support

• Scientific literature confirms that 4-Butylresorcinol is one of the most effective tyrosinase inhibitors tested on human skin models.

• Internal lab data shows that a 0.3% concentration provides a visible reduction in the intensity of stubborn dark spots within 8 weeks of use.

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