Allantoin
Essential Catalyst for Cell Regeneration and the Ultimate Partner for Licorice Actives
Allantoin is a classic, nature-identical compound renowned for its dual-action ability to soothe irritation while actively promoting tissue repair. Refined to pharmaceutical-grade purity by Shaanxi Huatai Bio-fine Chemical Co., our Allantoin acts as a biological “bridge” between protection and regeneration. It is particularly famous for its synergistic relationship with Licorice extracts (such as Dipotassium Glycyrrhizinate), where it enhances the soothing effect while simultaneously stimulating the growth of healthy new tissue.
| CAS No. | 97-59-6 |
|---|---|
| Source | High-Purity Synthesis (Bio-identical) |
| Appearance Color | White Crystalline Powder |
| Key Parameter | Purity >= 99.0% / Loss on Drying <= 0.5% |
| Solubility | Sparingly soluble in water; insoluble in oils and alcohol |
1. Key Specifications & Technical Parameters (Commercial Comparison)
| Feature | Shaanxi Huatai Standard | Market Advantage |
| Purity (HPLC) | >= 99.0% (Ultra-Pure) | Minimal impurities ensure high stability and zero skin irritation |
| Regenerative Power | Direct Keratolytic Action | Softens keratin more effectively than generic urea-based alternatives |
| Synergy Efficiency | Optimized for Licorice Blends | Proven to boost the soothing efficacy of botanical flavonoids |
| Safety Standard | USP/EP Grade Compliant | Globally recognized as safe (GRAS) for all ages, including infants |
| Particle Size | Ultra-fine Micronized Powder | Improved dissolution speed in water-based formulations |
| Non-Irritant Index | Zero Skin Sensitivity | Acts as an anti-irritant, masking the harshness of other actives |
2. Biological Mechanism of Action (MoA)
Our Allantoin operates through three primary pathways:
Cell Proliferation Stimulation: Promotes the rapid renewal of the skin’s basement membrane and epidermal layers, speeding up the healing of minor abrasions, acne scars, and environmental damage.
Keratolytic Softening: Increases the water-binding capacity of the extracellular matrix and promotes the shedding of dead skin cells (desquamation), leading to a smoother, softer texture.
Anti-Irritant Shield: Forms a temporary protective complex with sensitizing agents, significantly reducing the skin’s inflammatory response to surfactants, fragrances, or acids.
3. Formulation & Processing Guidelines
| Parameter | Recommended Standard | Formulation Tip |
| Usage Level | 0.1% to 0.5% (Standard) | Standard dosage for daily soothing and moisture |
| Intensive Healing | Up to 2.0% | Optimized for specialized hand creams and post-shave balms |
| Optimal pH Range | 3.0 to 8.0 | Extremely stable across a broad pH spectrum |
| Processing Temp | Below 80°C | Add to the water phase; stir well to ensure complete dissolution |
| Solubility Note | Water-Phase | Limited solubility (approx. 0.5% at 25°C); do not exceed solubility limit |
4. Market Advantages & Synergies
The “Perfect Partner”: When paired with Licorice Root Extract (Glabridin or Glycyrrhizinate), it creates a powerful anti-inflammatory duo that treats both the symptom (redness) and the damage (tissue loss).
Cost-Effective Luxury: Provides high-end “clinical healing” claims and a premium skin-feel for a very competitive raw material cost.
Multi-Category Versatility: Essential for everything from baby care and sensitive face masks to high-potency chemical peels (to offset irritation).
Recommended Synergistic Blends:
Allantoin + Licorice Extract (GHK-Cu): The gold standard for soothing inflamed or “burning” skin.
Allantoin + Panthenol (B5): A powerful hydration and healing team for barrier repair.
Allantoin + Salicylic Acid: Minimizes the dryness and irritation associated with BHA while smoothing skin texture.
5. Quality Assurance & Regulatory Support
Certifications: Manufactured in an ISO 9001 and ISO 22000 certified facility.
Technical Dossier: We provide complete TDS, MSDS, and COA to support global regulatory compliance and dermatological claims.
Applications: Ideal for soothing lotions, acne treatments, post-procedure creams, lip balms, and sun-care products.
6. Partner with Shaanxi Huatai Bio-fine Chemical Co.
Request a Technical Dossier: Access full purity certificates and dissolution guides.
Apply for a Free Sample: Experience the silkiness and soothing power of our 99% pure Allantoin.
Customized Quote: Discuss bulk pricing and pre-blended soothing solution options.
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