A Pure Water-Soluble Active Ingredient for Effective Skin Lightening
Alpha-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a pure water-soluble, biosynthetic active ingredient. It blocks epidermal melanin synthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. It is a functional active ingredient for skin lightening, ensuring an even and lighter skin tone, reducing the degree of skin tanning after UV exposure, and helping to minimize the appearance of liver spots. It is faster and more effective than kojic acid and leaves hydroquinone in the shade.
| CAS No. | 84380-01-8 |
|---|---|
| Source | Biosynthetic |
| Appearance | White Powder |
| Active Content (HPLC) | 98 Percent |
| Core Function | Skin Whitening, Anti-Freckle, Anti-inflammatory, Anti-bacterial |
| Solubility | Water |
For prestige beauty brands and contract manufacturers, the primary challenge in brightening is not just finding an inhibitor, but achieving “clinical-grade clarity” without the instability of legacy agents like Kojic Acid or the safety concerns of Hydroquinone. Most whitening ingredients suffer from rapid degradation in aqueous solutions, leading to discolored end-products and inconsistent efficacy. Our 98% High-Purity Alpha Arbutin, produced via precision biosynthesis, provides the ultimate stability-performance breakthrough. By ensuring a contaminant-free, highly stable profile, we empower your formulations to deliver superior depigmentation that remains potent throughout the product’s shelf life, setting a new benchmark for high-performance brightening lines.
Superior Tyrosinase Inhibition: Head-to-head comparative studies confirm that at a 1% usage level, Alpha Arbutin delivers a faster and more pronounced skin-lightening effect than both Kojic Acid and Beta-Arbutin.
Clinical Liver Spot Minimization: In a 3-month trial of 40 volunteers, a 2% Alpha Arbutin treatment resulted in significant improvement of liver spots in over 50% of cases, drastically outperforming Beta-Arbutin groups in both speed and visual reduction.
Unmatched Aqueous Stability: Engineered for long-term reliability, our Alpha Arbutin maintains an active half-life of at least 23 months when tested at 40°C in a 10% aqueous solution, ensuring your formulas retain their efficacy from the warehouse to the consumer’s vanity.
Broad-Spectrum pH Resilience: Exhibits exceptional stability across a critical pH range of 3.5–6.5, allowing for seamless integration into a diverse array of advanced serum and emulsion architectures.
| Parameter | Specification |
| Active Marker | 98% High-Purity Alpha Arbutin |
| Physical Form | Fine White Powder |
| Solubility | Water soluble |
| Recommended Dosage | 0.5% – 1.0% |
| pH Stability | 3.5 – 6.5 |
| Shelf Life | 24 Months |
| Storage | Tightly sealed, cool, dry, ventilated area |
Accelerate your R&D pipeline with these strategically optimized pairings designed to deliver market-leading, high-intensity brightening results:
The “Luminous-Clarity” Serum: Combine with Niacinamide and Ascorbyl Glucoside. This triple-action protocol targets pigment at three distinct stages; Alpha Arbutin inhibits the initial tyrosinase activity, Ascorbyl Glucoside provides sustained antioxidant brightening, and Niacinamide prevents the transfer of melanin to the surface.
The “Structural-Depigmentation” Cream: Pair with Tranexamic Acid. This synergy is the industry standard for stubborn hyperpigmentation; Alpha Arbutin focuses on enzymatic inhibition, while Tranexamic Acid addresses the inflammatory/vascular triggers of pigment formation, creating a comprehensive “prevention + correction” solution.
The “Overnight Radiance” Mask: Integrate with Hyaluronic Acid and Lactic Acid. This formula uses Alpha Arbutin to treat spots while the Lactic Acid gently refines the surface for better penetration, and Hyaluronic Acid ensures the skin remains plump and nourished throughout the brightening treatment.
Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:
ISO 9001
ISO 22000
COSMOS
HALAL
IQNET
Our comprehensive technical dossier—including TDS, MSDS, and COA—is available to support your regulatory and safety assessment requirements.
True innovation requires moving beyond legacy whitening agents toward standardized, high-purity bioactives that offer reproducible results. Do not let ingredient instability compromise the clinical integrity of your whitening line. Integrate the standardized reliability of our 98% Alpha Arbutin into your next-generation radiance formulations.
Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of technical validation reports and stability testing data.
Request your technical dossier and high-purity, odorless samples today to initiate the next generation of high-potency, stable skin-lightening care.
Room 1901, Building 2, Wanda Plaza, Beilin District, Xi'an, Shaanxi.
Copyright © 2026. Shaanxi Huatai Bio-Fine Chemical Co., Ltd. All Rights reserved.