DL-Panthenol

DL-Panthenol is a Provitamin B5 that is readily converted to Pantothenic Acid (Vitamin B5) within the skin and hair. It offers powerful deep moisturization and conditioning, promotes anti-inflammatory action and wound healing on the skin, and provides lasting repair and split-end prevention for hair, making it a highly versatile and essential ingredient for skincare and haircare.

INCI Name

Panthenol

CAS No.

16485-10-2 (DL-Panthenol)

Purity/Content

99%-102% (D-Panthenol equivalent)

Structure

Racemic mixture (50% D-Panthenol, 50% L-Panthenol)

Core Function

Moisturizing, Repairing, Conditioning, Anti-inflammatory

1. Product Overview & Market Relevance

DL-Panthenol is the racemic mixture of D-Panthenol (the biologically active form) and L-Panthenol (the inactive form). It functions as a humectant and moisturizer in cosmetics. Upon topical application, the active D-form is converted into Pantothenic Acid, a crucial component of Coenzyme A, vital for skin barrier function, tissue repair, and cellular metabolism. It is a fundamental ingredient used across high-volume cosmetic sectors including body care, face care, and premium hair care.

2. Technical Highlights and Critical Parameters

2.1 Mechanism of Action

  • Skin & Tissue Repair: Converted into Pantothenic Acid, it accelerates cell proliferation, supports wound healing, and strengthens the skin barrier.

  • Deep Hydration: Acts as an effective humectant, penetrating the stratum corneum to deliver and retain moisture deep within the skin and hair shaft.

  • Hair Shaft Thickening: Its moisturizing effects cause the hair shaft to swell, resulting in visibly thicker and more voluminous hair.

2.2 Standard Technical Specifications

ParameterSpecification (Standard Grade)
AppearanceClear, viscous liquid
pH (10% aq. solution)4.0-7.0
Recommended Dosage0.5%-5%
SolubilitySoluble in water, alcohol, propylene glycol
StorageStore in a cool, dry, dark place
StabilityHighly stable under normal formulating conditions

3. Market Positioning and Core Advantages

  • Proven Efficacy: Well-established cosmetic ingredient with decades of proven clinical efficacy for skin repair and deep conditioning.

  • Dual-Action Versatility: Equally effective for skin (barrier repair, anti-inflammatory, moisturizing) and hair (moisturizing, conditioning, anti-split end, volumizing).

  • High Bioavailability: Readily absorbed by both skin and hair, ensuring the conversion to the active Vitamin B5 form is efficient.

  • Safety and Tolerability: Extremely safe and non-irritating, suitable for sensitive skin and baby care products.

4. Formulation Guidelines

  • Integration Phase: DL-Panthenol is a water soluble liquid and should be added to the aqueous phase of the formulation after the heating process, when the batch temperature is below 40°C.

  • Concentration: Typical usage is 0.5%-5%, depending on the desired effect (e.g., higher concentrations for intensive repair or deep conditioning masks).

  • pH Control: Ensure the finished product pH is maintained between 4.0 and 7.0 for optimal stability.

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials include:

  • COSMOS (Natural and Organic Cosmetic Standard)

  • ISO 9001 Quality Management System

  • ISO 22000 Food Safety Management System

  • HALAL Certification

  • IQNET (The International Certification Network)

  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

  • Skincare: Moisturizers, lotions, sun-repair products (after-sun), anti-inflammatory creams, and wound healing formulations.

  • Haircare: Shampoos, conditioners, hair masks, styling products, and leave-in treatments for volume and split-end prevention.

  • Nail Care: Products for moisturizing and improving nail flexibility.

  • Baby & Sensitive Care: Gentle formulations requiring high moisturizing and soothing properties.

7. Scientific Evidence Summary

  • Wound Healing: Studies confirm that D-Panthenol (the active form) accelerates the regenerative process of the epidermis, supporting the repair of damaged skin.

  • Moisture Retention: DL-Panthenol is an excellent humectant that significantly improves the skin’s hydration level by reducing Trans-Epidermal Water Loss (TEWL).

  • Hair Conditioning: Due to its low molecular weight, it easily penetrates the hair cuticle, providing deep, long-lasting conditioning that enhances shine and reduces static electricity.

8.Frequently Asked Questions

Q1: What is the difference between DL-Panthenol and D-Panthenol?

A: DL-Panthenol is a racemic mixture containing 50% D-Panthenol (biologically active) and 50% L-Panthenol (inactive). D-Panthenol is the pure, biologically active form.

Q2: What is the recommended usage rate for hair conditioning products?

A: A dosage between 0.5%-5% is generally recommended across all applications, with higher concentrations often used in intensive hair masks and skin repair creams.

Q3: Does DL-Panthenol provide anti-aging benefits?

A: Yes. By moisturizing deeply and supporting the repair of the skin barrier, it helps the skin look smoother and fuller, indirectly reducing the appearance of fine lines caused by dehydration.

 

Source our High-Purity DL-Panthenol (Provitamin B5) for versatile, effective deep moisturizing, and powerful skin and hair repair formulations.

  • 🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

  • 🔬 Apply for a Free Sample: Test the stable, high-efficacy immune-boosting power of DL-Panthenol today.

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Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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