Glutathione (GSH), specifically the L-Reduced form, is a naturally occurring tripeptide (L–cysteine, L–glutamic acid, and glycine) often called the body’s “Master Antioxidant.” It is critical for cellular defense, detoxification, and immune function. Topically, GSH delivers powerful skin-lightening, anti-aging, and detoxification benefits by directly neutralizing free radicals and significantly shifting the melanin production pathway from dark (eumelanin) to light (pheomelanin) pigment.
| INCI Name | Glutathione |
|---|---|
| CAS No. | 70-18-8 |
| Source | Biotechnological Fermentation |
| Appearance | White crystalline powder |
| Core Function | Skin Brightening, Master Antioxidant, Cellular Detoxification, Anti-aging, Tyrosinase Inhibition |
In the competitive landscape of prestige skincare, the greatest hurdle to formulating with L-Glutathione is stability. While recognized globally as the “Master Antioxidant,” its extreme sensitivity to light, heat, and oxygen frequently results in inactive, degraded formulations that fail to deliver promised results. High-end brands demand more than just marketing claims; they require stability, purity, and clinical-grade bioavailability. Our 98% Ultra-Pure Reduced L-Glutathione provides the authoritative solution. By providing the biologically active GSH form at maximum purity, we empower R&D teams to bypass standard degradation issues and integrate a clinically proven powerhouse for detoxification, melanin modulation, and total cellular defense.
Melanin Modulation: Directly inhibits tyrosinase activity and shifts melanogenesis from dark eumelanin to light-reflecting pheomelanin, providing a clinically verifiable pathway to luminous, even skin tone.
Master Cellular Defense: Actively neutralizes ROS and prevents protein/lipid oxidative damage, serving as the essential co-factor for cellular detoxification and mitochondrial protection.
Antioxidant Recycling: Uniquely capable of regenerating and recycling spent Vitamin C and Vitamin E, significantly extending the effective lifespan of your formula’s foundational antioxidants.
Clinical Bioavailability: A naturally occurring tripeptide that guarantees superior skin biocompatibility, ensuring deep tissue penetration and a non-cytotoxic safety profile for sensitive skin.
| Parameter | Specification |
| Purity (Reduced Form) | >= 98.0% |
| Molecular Weight | 307.32 g/mol |
| Appearance | White Crystalline Powder |
| Solubility | Water Soluble |
| Recommended Dosage | 0.5% – 2.0% |
| pH Stability Range | 5.0 – 6.0 |
| Shelf Life | 24 Months |
| Storage | Store in a cool, dark, dry place (Inert gas protection recommended) |
Accelerate your R&D pipeline with these strategically optimized pairings designed for high-performance, resilient skincare:
The “Luminous Detox” Serum: Combine with Vitamin C Derivatives (e.g., Ascorbyl Glucoside). This is the ultimate synergy; Glutathione protects and recycles the Vitamin C, effectively doubling the formula’s anti-aging and brightening longevity while mitigating oxidative stress.
The “Total Repair” Antioxidant Cocktail: Pair with Ferulic Acid and Vitamin E. This three-tier antioxidant defense system addresses environmental pollution and UV-induced free radicals, providing an unparalleled barrier against urban “inflammaging.”
The “Post-Inflammatory Recovery” Complex: Integrate into formulas with Niacinamide. This blend accelerates the clearing of post-acne marks and pigment, as the Niacinamide improves barrier cohesion while the Glutathione stabilizes the melanin synthesis pathway.
Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:
ISO 9001
ISO 22000
COSMOS
HALAL
IQNET
Our comprehensive technical dossier—including TDS, MSDS, and COA—is available to support your regulatory and safety assessment requirements.
True efficacy requires the highest standards of molecular purity and stability. Do not settle for oxidatively compromised Glutathione that undermines your product’s potency. Elevate your formulation standards with our 98% Ultra-Pure Reduced L-Glutathione.
Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of clinical validation data and stability-enhancement guidance.
Request your technical dossier and premium-grade samples today to initiate the next generation of high-potency, master-antioxidant care.
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