Glyceryl Glucoside

The “Aquaporin Activator” for Deep Cellular Hydration

Brief Introduction: Glyceryl Glucoside is a high-performance multifunctional active ingredient known for its remarkable ability to stimulate the expression of Aquaporin-3 (AQP3). It acts as a powerful hydration booster that opens the skin’s water channels, ensuring deep-seated moisture delivery and long-lasting barrier repair.

CAS No.

22160-26-5 / 100402-60-6

Source

Natural Glyceryl Glucoside (Biotechnological Synthesis)

Appearance Color

Colorless to light yellow viscous liquid

Key Parameter

Purity up to 99% / Concentration 50% (Customizable)

Solubility

Water Soluble

1. Product Description

Glyceryl Glucoside is a high-performance multifunctional active ingredient that targets the skin’s internal hydration network. Originally identified in extremophile organisms for its stress-protection properties, it is now recognized as a premier “Aquaporin-3 (AQP3) Activator” in cosmetic science. It facilitates the transport of water and glycerol into the epidermis, providing “inside-out” irrigation that significantly outperforms surface-level humectants.


2. Key Specifications & Technical Parameters (Commercial Comparison)

SpecificationStandard GradePremium High-Purity Grade
Assay (Glyceryl Glucoside)≥ 50% Solution≥ 99% Pure Powder
Free Glycerol< 5%< 0.5%
pH (10% water solution)3.0 – 6.54.5 – 6.0
Heavy Metals< 10 ppm< 5 ppm
Microbial Content< 100 cfu/g< 10 cfu/g

3. Biological Mechanism of Action (MoA)

  • Aquaporin-3 Expression: It upregulates the AQP3 protein in keratinocytes, which acts as a “water channel” to ensure efficient hydration circulation across the cell membranes.

  • Osmotic Balance: Acts as a natural osmolyte, protecting cells from dehydration stress and maintaining cellular osmotic pressure.

  • ATP Stimulation: Boosts mitochondrial activity and ATP production, revitalizing aged or stressed skin cells for enhanced metabolic repair.


4. Formulation & Processing Guidelines

  • Dosage: Recommended use level is 0.5% – 2.0% for daily care, and up to 5.0% for intensive repair treatments.

  • Compatibility: Excellent compatibility with thickeners (Carbomer, Xanthan Gum), emulsifiers, and other actives like Vitamin C or Hyaluronic Acid.

  • Processing: Can be added directly to the water phase. Stable under high-temperature processing (up to 80°C) and effective across a wide pH range (pH 3–10).


5. Market Advantages & Synergies

  • Synergy with Hyaluronic Acid: While HA locks water on the surface, Glyceryl Glucoside opens the channels to pull moisture deeper, creating a 3D hydration effect.

  • Non-Sticky Sensory Profile: Provides a fresh, light skin feel compared to the heavy or tacky texture of high-concentration glycerin.

  • Clean Beauty Appeal: Derived from sustainable biotechnological processes, meeting the demand for “natural-identical” and high-efficacy ingredients.


6. Quality Assurance & Regulatory Support

  • Cosmetic Grade Only: Produced strictly for cosmetic applications, ensuring no pharmaceutical impurities or medicinal side effects.

  • Full Documentation: We provide comprehensive TDS, MSDS, COA, and Efficacy Test Reports (In-vitro/In-vivo).

  • Global Compliance: Fully compliant with INCI, REACH (EU), and NMPA (China) regulations for cosmetic raw materials.


7. Partner with Shaanxi Huatai Bio-fine Chemical Co.

Shaanxi Huatai Bio-fine Chemical Co., Ltd. is a leading global supplier of high-purity cosmetic-grade active ingredients. With our advanced biotechnology platform and rigorous quality control systems, we ensure that every batch of Glyceryl Glucoside meets the highest industrial standards.

  • Direct Factory Supply: Ensuring competitive B2B pricing and consistent stock availability for manufacturers.

  • Customized Solutions: Tailored concentrations and formulations to meet your specific product development needs.

  • Global Logistics: Professional handling and documentation for seamless international procurement.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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