Glycyrrhetinic Acid

The Gold Standard Triterpenoid for Soothing and Anti-Inflammatory Applications

Glycyrrhetinic Acid, also known as Enoxolone, is the metabolite of Glycyrrhizic Acid and a key triterpenoid active ingredient in licorice. Standardized to an ultra-high purity of 98 Percent (UV) and provided as a fine white powder, it is highly valued for its exceptional anti-inflammatory, anti-allergic, and soothing properties. Its lipophilic (oil-soluble) nature makes it ideal for superior skin penetration in high-end cosmetic and dermatological formulations.

CAS No.

471-53-4

Source

Licorice Root

Appearance

Fine White Powder

Active Content (Purity)

98 Percent

Core Function

Potent Anti-Inflammatory, Anti-Allergy, Soothing, Oil-Soluble Skin Repair

Solubility

Soluble in Oil, Ethanol, and Organic Solvents (Lipophilic)

The Architect of Skin Calm: 98% Ultra-Pure Glycyrrhetinic Acid for Clinical Efficacy

For luxury skincare brands, the struggle to balance potent anti-inflammatory performance with aesthetic elegance—colorless, odorless, and stable—often leads to formulation compromise. Our 98% High-Purity Glycyrrhetinic Acid eliminates that trade-off. This pharmaceutical-grade triterpenoid offers unmatched dermal penetration and rapid neutralization of skin reactivity. Designed for the most demanding sensitive-skin and post-procedural formulations, our ingredient delivers high-density soothing power in a perfectly white, fine-powder format that will not alter your product’s aesthetic identity.

Superior Performance: The Clinical Edge

  • Dermal-Penetrating Anti-Inflammatory: Its lipophilic triterpenoid structure ensures deep epidermal absorption, effectively modulating corticosteroid metabolism to provide near-instant relief from erythema and contact dermatitis.

  • Clinical-Grade Purity: Standardized at 98% purity, this active achieves therapeutic milestones at extremely low inclusion levels (0.05% – 1.0%), preserving the integrity of your luxury base.

  • Aesthetic Perfection: A crisp, white powder that integrates seamlessly into crystal-clear serums, white emulsions, and high-end dermatological creams without imparting discoloration or “herbal” odors.

  • Barrier Resuscitation: Beyond neutralizing immediate irritation, it actively supports the repair of damaged skin, making it an essential component for next-generation barrier-repair protocols.

Core Specifications & Technical Parameters

ParameterSpecification
Purity (HPLC/UV)>= 98%
AppearanceUniform Fine White Powder
OdorVery Faint, Characteristic
Particle Size100-200 Mesh
Loss on Drying<= 1.0%
Heavy Metals (as Pb)<= 10 ppm
Arsenic (As)<= 1 ppm
Recommended Use Rate0.05% – 1.0%
Shelf Life24 Months
StorageStore tightly sealed in a cool, dark, dry place

Formulation Intelligence: The “Golden Synergy” Blends

Accelerate your R&D process with these scientifically validated combinations designed for market-leading soothing performance:

  • The “Clinical Repair” Complex: Pair with Ceramides (NP/AP/EOP). This combination mimics the skin’s natural barrier while Glycyrrhetinic Acid lowers the inflammation threshold, creating an ideal treatment for compromised or post-peel skin.

  • The “Zero-Redness” Soothing Shield: Combine with Bisabolol. This dual-action approach targets both immediate heat-induced irritation and long-term redness, providing a comprehensive solution for rosacea-prone or highly reactive skin.

  • The “Post-Laser” Recovery Serum: Integrate with Panthenol and Madecassoside. The synergy between these three actives offers a profound recovery effect for skin subjected to professional aesthetic procedures.

Quality Assurance & Regulatory Excellence

Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:

  • COSMOS

  • ISO 9001

  • ISO 22000

  • HALAL

  • IQNET

Full technical dossiers, including TDS, MSDS, and COA, are available to support your regulatory and safety assessment requirements.

Elevate Your Soothing Formulations

Excellence in formulation begins with the purity of your raw materials. Stop settling for “extract-level” results when you can leverage the precision of 98% pure Glycyrrhetinic Acid.

Connect with our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our clinical efficacy data and stability study reports.

Request your technical dossier and premium-grade samples today to initiate the next generation of high-potency soothing care.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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