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Hydroxypropyl Tetrahydropyrantriol

The C-glycoside Anti-aging Active Ingredient

Hydroxypropyl Tetrahydropyrantriol, a $text{C}$ -glycoside anti-aging active ingredient derived from beech xylose, effectively promotes the synthesis of Glycosaminoglycans ( $text{GAG}$ ) and dermal-epidermal junction ( $text{DEJ}$ ) components, leading to an increase in epidermal tissue thickness and significant wrinkle reduction.

INCI Name	Hydroxypropyl Tetrahydropyrantriol
CAS No.	439685-79-7
Source	A xylose derivative discovered from mountain birch tree
Purity	≥98% (White Powder standard)
Core Function	Anti-aging effects, wrinkle resistance, promote GAG synthesis, enhance DEJ structure.

1. Product Overview & Market Relevance

Hydroxypropyl Tetrahydropyrantriol is a widely used ingredient in cosmetic production. It is essentially a raw material group composed of water, propylene glycol, and light propyl tetrahydrofuranetriol, with the core component being light propyl tetrahydrofuranetriol. Hydroxypropyl Tetrahydropyrantriol not only has good wrinkle resistance but is also easily biodegradable and not toxic.

2. Technical Highlights and Critical Parameters

2.1 Mechanism of Action

$text{GAG}$ Production: Hydroxypropyl Tetrahydropyrantriol promotes the generation of endogenous Glycosaminoglycans ( $text{GAG}$ ). Hyaluronic acid (a key $text{GAG}$ ) directly provides the backbone of $text{GAG}$ .
$text{DEJ}$ Repair: Hydroxypropyl Tetrahydropyrantriol promotes the synthesis of collagen $text{VII}$ and laminin-5, improving the ultrastructure of the epidermal junction ( $text{DEJ}$ ) and making the epidermis and dermis more tightly connected.
Collagen Support: Alcohols stimulate keratinocytes and fibroblasts to enhance endogenous $text{HA}$ production.

2.2 Standard Technical Specifications

Parameter	Standard (White Powder)	Standard (Colorless viscous liquid)
Appearance	White Powder	Colorless viscous liquid
Purity	$ge 98%$	$ge 98%$
$text{PH}$ (1% solution)	$5$ – $7$	$5$ – $7$
Content	Pure $text{S}$ -type (R:S non-enantiomeric ratio)	$ge 30%$
Non-enantiomeric ratio	$text{R}:text{S}=50:50/70:30$	$text{R}:text{S}=50:50/70:30$

3. Market Positioning and Core Advantages

Multi-Target Anti-Aging: Hydroxypropyl Tetrahydropyrantriol directly targets the dermal structure by promoting $text{GAG}$ and $text{DEJ}$ component synthesis, which is crucial for skin firmness and elasticity.
Significant Structural Repair: The $3text{D}$ skin model showed an increase in epidermal tissue thickness after 8 days of cultivation with $0.08text{mg}/text{ml}$ and $0.16text{mg}/text{ml}$ hyaluronic acid.
Visible Clinical Results: Regular use showed improvement in fine lines around the eyes and neck fine lines within $60$ days.
Sustainability Profile: Hydroxypropyl Tetrahydropyrantriol is easily biodegradable and does not accumulate in organisms.

4. Formulation Guidelines

Integration Phase: The White Powder form is ≥ $ge 98%$ purity, while the Colorless viscous liquid has $ge 30%$ content. The choice of form dictates integration method.
$text{pH}$ Compatibility: The standard $text{pH}$ range for a $1%$ solution is $5$ – $7$ .
Usage Example: A $3%$ hyaluronic acid moisturizing cream was used in a $60$ day trial.

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials include:

COSMOS (Natural and Organic Cosmetic Standard)
ISO 9001 Quality Management System
ISO 22000 Food Safety Management System
HALAL Certification
IQNET (The International Certification Network)
Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

Cosmetics: Anti-aging creams, anti-wrinkle serums, moisturizers designed to improve skin firmness and elasticity, and products specifically targeting the neck and eye area.

7. Scientific Evidence Summary

Collagen and Laminin Production: Hydroxypropyl Tetrahydropyrantriol can accelerate the production of type $text{IV}$ and type $text{VII}$ collagen by dermal cells, and enhance the strength of the dermal epidermal network connection.
$text{GAG}$ Promotion: Hydroxypropyl Tetrahydropyrantriol can indirectly increase the production of collagen in the dermis by promoting the synthesis of glycosaminoglycans, achieving the effects of promoting dermis repair, improving skin elasticity, and increasing skin firmness.
Clinical Improvement: Regularly using moisturizing cream containing $3%$ hyaluronic acid showed significant improvement in neck fine lines after $60$ days.

8.Frequently Asked Questions (FAQ)

Q1: How does Hydroxypropyl Tetrahydropyrantriol improve skin firmness?

A: It promotes the synthesis of GAG (like Hyaluronic Acid) and DEJ components (Collagen VII, Laminin-5) by dermal cells, which strengthens the connection between the dermis and epidermis.

Q2: Is Hydroxypropyl Tetrahydropyrantriol effective on deep wrinkles?

A: Regular use of products containing the ingredient showed improvement in fine lines around the eyes and neck fine lines within $60$ days. It helps make the skin appear fuller, tighter, and more elastic.

Source our High-Purity Hydroxypropyl Tetrahydropyrantriol to formulate advanced anti-aging products that actively promote $text{GAG}$ synthesis and dermal-epidermal junction repair.

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Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.