Potassium Azeloyl Diglycinate

The Water-Soluble Azelaic Acid Derivative for Dual-Action Sebum Control and Brightening

Potassium Azeloyl Diglycinate (PAD) is a high-performance cosmetic-grade derivative of Azelaic Acid. Known for its exceptional water solubility and skin tolerance, it provides a sophisticated solution for managing oily, acne-prone skin while simultaneously promoting a brighter, more even skin tone. Unlike pure Azelaic Acid, PAD offers significant moisturizing benefits and is effortlessly incorporated into diverse skincare formulations.

CAS No.

473728-74-0

Source

High-Purity Cosmetic Synthesis

Appearance Color

Colorless to Light Yellow Clear Liquid

Key Parameter

Active Content: 28.0% – 32.0%

Solubility

Highly Water-Soluble

Shaanxi Huatai Bio-fine Chemical Co. offers Potassium Azeloyl Diglycinate (PAD) as a breakthrough solution to the formulation limitations of traditional Azelaic Acid. Our exclusive advantage lies in achieving the perfect balance of high concentration and stability by chemically bonding Azelaic Acid with Glycine, which dramatically enhances water solubility and skin feel. This cosmetic-grade active excels in sebum regulation and anti-acne performance while providing unique moisturizing benefits that prevent the dryness associated with standard Azelaic Acid. For brands seeking minimalist yet high-efficacy formulas, our PAD is the ideal core ingredient for oily skin repair and full-spectrum brightening.

1. Product Overview & Key Specifications

Potassium Azeloyl Diglycinate is a multi-functional active that combines the physiological properties of Azelaic Acid with the hydrating functions of Glycine. It is a gentle ingredient specifically suited for treating excessive sebum production, dullness, and inflammatory skin tones.

2. Technical Highlights & Critical Parameters

Our production process ensures that PAD remains stable across a wide pH range and is resistant to interference from metal ions.

  • pH (direct measurement): 6.5 – 8.5

  • Active Content: 30.0% ± 2.0%

  • Heavy Metals: < 10 ppm

  • Microbiological Status: Complies with international cosmetic hygiene standards.

3. Mechanism of Action (MoA)

  • Sebum Regulation: Competitively inhibits 5α-reductase to reduce excessive oil production from the sebaceous glands.

  • Brightening: Inhibits tyrosinase activity to reduce melanin synthesis and improves post-inflammatory hyperpigmentation.

  • Barrier Optimization: The glycine component increases skin water content and helps repair the damaged skin barrier.

4. Core Advantages & Market USPs

  • Superior Water Solubility: Solves the common issues of poor solubility and precipitation seen with pure Azelaic Acid, allowing for direct addition to aqueous systems.

  • High Safety & Gentleness: Very low skin irritation, making it suitable for long-term care and oily-sensitive skin types.

  • Clean Skin Feel: Provides a non-sticky finish that improves the transparency and light texture of the final product.

5. Formulation Guidelines

  • Recommended Usage: 2.0% – 8.0%.

  • Processing: Highly water-soluble; recommended to be added during the cold-process phase or below 40°C in the final stage of emulsification.

  • pH Compatibility: Stable within a range of 5.0 – 9.0; suggested final product pH is 6.0 – 7.5.

6. Quality Assurance & Regulatory Confidence

Our manufacturing facility is ISO 9001/22000 and HALAL certified. As a high-purity cosmetic-grade raw material, PAD complies with global regulatory requirements, supported by complete COA, TDS, and MSDS documentation.

7. Recommended Synergistic Combinations

  1. PAD + Niacinamide: A golden duo for oil control and brightening, effectively refining large pores.

  2. PAD + Totarol / Salicylamide: Enhances anti-acne efficacy, targeting both comedones and inflammation.

  3. PAD + Ectoin: Provides deep repair while controlling oil, perfect for oily-sensitive skin relief.

8. Typical Applications & Success Stories

PAD is widely utilized in “Oil-Control Balancing Toners,” “Acne-Regulating Serums,” and “Lightweight Brightening Creams.” Many star products targeting Asian oily skin types feature our PAD as the core functional ingredient.

9. Scientific Evidence & Literature Support

Laboratory tests show that after using a formula containing 3% PAD for 3 weeks, skin sebum levels decreased by an average of over 25%, while skin hydration significantly increased. Scientific literature supports its efficacy in improving rosacea and post-inflammatory hyperpigmentation.


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Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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