Sodium Polyglutamate
Advanced NMF Activation and Film-Forming Hydration Surpassing Hyaluronic Acid
Sodium Polyglutamate is a revolutionary biopolymer that represents the next generation of hydration technology. Produced through precision fermentation by Shaanxi Huatai Bio-fine Chemical Co., y-PGA is not just a surface humectant; it is a biological “moisture manager.” With a water-holding capacity significantly higher than Hyaluronic Acid (HA), it forms a breathable, silky film that locks in moisture while actively stimulating the skin’s own Natural Moisturizing Factors (NMFs). It is the premier choice for luxury formulations seeking a non-sticky, high-performance “glass skin” finish.
| CAS No. | 28829-38-1 |
|---|---|
| Source | High-Purity Microbial Fermentation (Bacillus subtilis) |
| Appearance Color | White to Off-white Powder or Granules |
| Key Parameter | Purity >= 92.0% / Multiple MW Options (High/Medium/Low) |
| Solubility | Highly Water-soluble |
1. Key Specifications & Technical Parameters (Commercial Comparison)
| Feature | Shaanxi Huatai Standard | Market Advantage |
| Water Retention | > 5,000x its own weight | Superior hydration capacity compared to traditional HA |
| Skin Feel | Silky & Non-tacky | Provides a smooth, elegant finish without the “sticky” HA residue |
| NMF Activation | Stimulates PCA & Lactic Acid | Actively increases internal skin moisture from within |
| Molecular Stability | High Enzyme Resistance | More resistant to skin hyaluronidase; provides longer-lasting hydration |
| Film-Forming | Micro-Elastic Shield | Forms a breathable barrier that protects against environmental pollutants |
| Brightening Support | Tyrosinase Inhibition | Naturally helps maintain an even skin tone by inhibiting melanin |
2. Biological Mechanism of Action (MoA)
Our Sodium Polyglutamate operates through three primary pathways:
NMF Synthesis Activation: Unlike external humectants, $gamma$-PGA penetrates the epidermis to signal the production of pyrrolidone carboxylic acid (PCA), lactic acid, and urocanic acid, boosting the skin’s innate hydration system.
Elasticity Protection: Inhibits the activity of hyaluronidase (the enzyme that breaks down your natural Hyaluronic Acid), thereby preserving the skin’s internal moisture scaffold and bounce.
Controlled Nutrient Delivery: Its unique polymeric structure can “trap” other active ingredients and water molecules, slowly releasing them into the skin for prolonged efficacy and a sustained “plumping” effect.
3. Formulation & Processing Guidelines
| Parameter | Recommended Standard | Formulation Tip |
| Usage Level | 0.05% to 1.0% (Standard) | High efficacy; a small amount significantly alters skin feel |
| Intensive Hydration | Up to 2.0% | Optimized for premium “Water-Bomb” masks and serums |
| Optimal pH Range | 5.0 to 8.0 | Stable in the most common professional skincare ranges |
| Processing Temp | Below 80°C | Add to the water phase; heat-stable but avoid prolonged boiling |
| Compatibility | High Electrolyte Tolerance | More stable in formulations containing salts than Hyaluronic Acid |
4. Market Advantages & Synergies
The “HA Upgrade”: Perfect for brands looking to differentiate themselves from the crowded Hyaluronic Acid market with a “Higher-Tech” hydration story.
Instant Sensory Impact: Provides an immediate silky, smooth skin feel that consumers can feel during the first application, boosting product “perceived value.”
“Glass Skin” Finisher: Ideal for daytime serums and primers as it creates a smooth, reflective surface that enhances makeup application.
Recommended Synergistic Blends:
Sodium Polyglutamate + Hyaluronic Acid: Creates a multi-layered hydration network (HA for deep plumping, PGA for film-locking and NMF boost).
Sodium Polyglutamate + Sodium DNA: Combines advanced moisture management with DNA-level structural repair.
Sodium Polyglutamate + Panthenol (B5): Provides an intensive barrier-recovery system for dehydrated or post-procedure skin.
5. Quality Assurance & Regulatory Support
Certifications: Manufactured in an ISO 9001 and ISO 22000 certified facility.
Technical Dossier: We provide complete TDS, MSDS, and COA to support global regulatory compliance and performance claims.
Applications: Ideal for “Plumping” serums, silky hydration lotions, moisture-lock masks, and premium primers.
6. Partner with Shaanxi Huatai Bio-fine Chemical Co.
Request a Technical Dossier: Access full water-retention data and MW comparison reports.
Apply for a Free Sample: Experience the silky texture of our high-purity Sodium Polyglutamate.
Customized Quote: Discuss bulk pricing and tailored molecular weight distributions.
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