Dipotassium Glycyrrhizinate

The Premium Natural Soothing & Anti-inflammatory Agent

A highly safe and effective natural plant component known for its potent anti-inflammatory, soothing, and antibacterial properties. DG promotes skin recovery, reduces sensitivity, and is recognized globally for its high safety profile in cosmetic and personal care applications.

CAS No.

68797-35-3

Source

Natural Plant Extract (Licorice Root)

Appearance Color

White Powder

Key Efficacy

Anti-inflammation, Soothing, Anti-irritation, Antibacterial

Purity

Up to 99% (High Purity Powder)

Solubility

Water-Soluble

The Anti-Irritation Benchmark: High-Purity Dipotassium Glycyrrhizate

In the prestige skincare and dermatological market, the most significant barrier to active ingredient efficacy is the inflammatory response. Modern consumers are increasingly using high-potency actives like Retinoids, AHAs, and high-concentration Vitamin C, which often compromise the skin barrier and incite chronic irritation, stinging, and redness. For luxury brands, an inflamed skin environment negates the benefits of expensive anti-aging actives and compromises brand loyalty. Our 99% High-Purity Dipotassium Glycyrrhizate is the essential, clinical-grade solution to this problem. Sourced from natural licorice root and manufactured to the strictest heavy-metal standards, our DG offers more than just “soothing”—it provides an active, regulatory-compliant barrier-shield that allows your high-potency formulas to deliver transformational results without the side effects of irritation.

Unrivaled Efficacy: Clinical & Laboratory Proof

  • Clinical Irritation Mitigation: In human volunteer trials using Sodium Dodecyl Sulfate (SDS) as an irritant, the application of our Dipotassium Glycyrrhizate demonstrated a clear concentration-dependent reduction in thermal discomfort, stinging, and erythema. A 0.7% inclusion level showed the most optimal clinical improvement in mitigating irritation markers.

  • Regulatory-Grade Safety: Recognized as Generally Recognized As Safe (GRAS) by the US FDA, our DG provides the highest tier of formulation safety. It is clinically validated to be non-penetrative, non-toxic, and non-irritating, ensuring complete compatibility even for sensitive, atopic, or pediatric skin.

  • Heavy-Metal Precision: Manufactured to the most rigorous Japanese cosmetic standards, our DG offers exceptional purity with heavy-metal levels strictly controlled far below global regulatory thresholds, ensuring total supply chain compliance for international export.

Core Specifications & Technical Parameters

GradePhysical FormSolubilityRecommended Use LevelShelf Life
73%White PowderWater-Soluble0.1% – 5.0%24 Months
75%White PowderWater-Soluble0.1% – 5.0%24 Months
99%White PowderWater-Soluble0.1% – 5.0%24 Months

Formulation Intelligence: The “Golden Synergy” Blends

Accelerate your R&D pipeline with these strategically optimized pairings designed to deliver market-leading, high-tolerance results:

  • The “Retinoid-Comfort” Night System: Combine DG with Encapsulated Retinol. This synergy allows you to market high-potency Vitamin A results without the “Retinoid burn.” DG manages the inflammatory response at the skin surface, allowing the Retinol to drive cellular turnover while maintaining complete comfort.

  • The “Post-Procedure” Barrier Repair: Pair DG with Centella Asiatica Extract. This combination is the industry gold standard for post-laser or post-peel recovery; DG provides immediate relief from heat and stinging, while Centella Asiatica accelerates the tissue-healing process.

  • The “Hydration-Security” Protocol: Integrate with Hyaluronic Acid. By pairing DG with multi-molecular HA, you go beyond simple surface moisture. The DG maintains the integrity of the HA-rich environment by preventing inflammatory degradation, resulting in a more sustained, “plumped” aesthetic for the consumer.

Quality Assurance & Regulatory Excellence

Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:

  • ISO 9001

  • ISO 22000

  • COSMOS

  • HALAL

  • IQNET

Our comprehensive technical dossier—including TDS, MSDS, and COA—is available to support your regulatory and safety assessment requirements.

Secure Your Competitive Edge in Skin Comfort

True innovation in high-end skincare requires the integration of high-purity, standardized bioactives that serve as the “safety net” for your active ingredient portfolio. Stop settling for low-grade licorice extracts that introduce impurities into your luxury formulations. Integrate the standardized reliability of our 99% High-Purity Dipotassium Glycyrrhizate into your next generation of high-potency, irritation-free skin care.

Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of technical validation reports and stability testing data.

Request your technical dossier and high-purity, premium-grade samples today to initiate the next generation of high-potency, soothing anti-irritation care.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

Laissez un message