In the competitive world of dermo-cosmetics, few ingredients have seen a resurgence as significant as Mandelic Acid. Often associated with the pioneering clinical work of vivant mandelic acid formulations, this alpha hydroxy acid (AHA) has redefined how the industry treats acne, hyperpigmentation, and aging in sensitive skin. Derived from bitter almonds, Mandelic Acid is an aromatic AHA that bridges the gap between effective resurfacing and skin barrier preservation.
For professional formulators, the efficacy of an active ingredient is directly proportional to its purity and molecular integrity. Based on industry-leading production data, high-grade Mandelic Acid must meet the following pharmaceutical standards:
| Parameter | Specification / Value |
| Product Name | Mandelic Acid |
| CAS Number | 90-64-2 |
| Purity (HPLC) | 99.0% |
| Appearance | White crystalline powder |
| Molecular Formula | C_{8}H_{8}O_{3} |
| Molecular Weight | 152.15{ g/mol} |
| Melting Point | 119.0 – 121.0 |
| Solubility | Soluble in water, isopropyl alcohol, and ethanol |
| Heavy Metals | 10 ppm |
The defining characteristic of Mandelic Acid is its molecular size. With a molecular weight of 152.15 g/mol, it is significantly larger than Glycolic Acid (approx. 76\text{ g/mol}). This physical property is the foundation of the vivant mandelic acid philosophy.
Beyond simple exfoliation, Mandelic Acid serves as a multi-functional powerhouse in clinical settings.
Mandelic Acid is uniquely lipophilic compared to other AHAs. This allows it to bypass the oily sebum in the pores to deliver its natural antibacterial benefits. In clinical cases, 99.0% pure Mandelic Acid has been shown to reduce acne lesions more effectively than some traditional topical antibiotics, without the risk of bacterial resistance.
Mandelic Acid acts as a mild tyrosinase inhibitor. When used in 10% to 20% concentrations, it targets melasma and age spots by breaking down the bonds between surface pigment cells while simultaneously slowing the production of new melanin.
With a melting point of high solubility in both alcohol and water, it provides exceptional formulation flexibility. It is frequently paired with Salicylic Acid for acne-prone skin or with L-Ascorbic Acid for comprehensive anti-aging regimens.
The demand for “barrier-friendly” exfoliation has driven a 15% annual increase in Mandelic Acid-based product launches. As consumers move away from “aggressive peeling” and toward “skin longevity,” the role of high-purity (CAS 90-64-2) actives becomes paramount.
By utilizing Mandelic Acid with a purity of 99.0% and heavy metal content 10 ppm, brands can guarantee a product that is both high-performance and dermatologically safe. Whether used in a professional chemical peel or a daily corrective serum, Mandelic Acid remains the undisputed “intelligent acid” of the 21st century.
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