Ergothioneine is a naturally occurring, sulfur-containing amino acid derivative and a powerful, “smart” antioxidant that is actively transported into cells via a specific transporter (OCTN1). Its key efficacy lies in its exceptional cellular protection against oxidative stress (ROS), its unique ability to mitigate UV and blue light damage, and its proven role in preserving DNA and mitochondrial health. It is a cutting-edge, high-stability active ingredient for premium anti-photoaging, DNA defense, and longevity formulations in both topical and ingestible forms.
| Plant Source | Mushrooms |
|---|---|
| Extract Purity | 98% or higher |
| Appearance | White to off-white powder |
| CAS Number | 497-30-1 |
| Molecular Formula | C9H15N3O2S |
| Molecular Weight | 227.3 g/mol |
| EINECS Number | 207-850-8 |
In the prestige skincare and dermatological market, formulators are facing a fundamental challenge: legacy antioxidants like Vitamin C and E are “outside-the-cell” protectors that oxidize rapidly and fail to reach the deep, inner-cellular machinery where damage truly occurs. For high-end brands, this is a significant performance bottleneck. Consumers are increasingly sophisticated, demanding “deep-cellular” protection that encompasses blue-light defense, DNA safeguarding, and mitochondrial support. Our 98%+ High-Purity Ergothioneine (EGT) is the clinical-grade breakthrough your pipeline requires. By leveraging the unique OCTN1 active transport mechanism, EGT is the only antioxidant that actively concentrates within the mitochondria and nucleus—the ground zero of skin aging—to provide unparalleled, stable, and durable cellular defense.
Active Transmembrane Transport: Uniquely recognized by the OCTN1 transporter, EGT is selectively imported into the cell, reaching peak concentrations in the mitochondria and nucleus—a feat no other conventional antioxidant can match.
Superior Singlet Oxygen Quenching: Laboratory assays confirm EGT’s exceptional efficiency in neutralizing singlet oxygen and hydroxyl radicals induced by UV radiation and High-Energy Visible (HEV) Blue Light, providing a robust defense against photo-aging.
Genomic & Mitochondrial Stabilization: By buffering oxidative stress at the nuclear and mitochondrial level, EGT protects cellular DNA integrity and preserves enzymatic function, directly inhibiting the pathway of premature senescence.
Extreme Formulation Stability: Unlike unstable Vitamin C, EGT remains remarkably inert under high-heat processing and long-term storage, ensuring that the potency your R&D team formulates in the lab is the exact potency the consumer experiences.
| Parameter | Specification |
| Active Marker | ≥98% Purity (Enzymatic Assay) |
| Physical Form | Fine White Crystalline Powder |
| Solubility | Highly water soluble |
| Recommended Dosage | 0.01% – 0.5% |
| pH Stability | 4.0 – 7.5 |
| Shelf Life | 24 Months |
| Storage | Cool, dark, and moisture-proof environment |
Accelerate your R&D pipeline with these strategically optimized pairings designed to deliver market-leading, “smart-protection” results:
The “Digital-Defense” Serum: Combine with Ferulic Acid. This is the ultimate “Anti-Pollution & Anti-Blue Light” protocol; EGT provides the intracellular shielding against HEV radiation, while Ferulic Acid acts as the extracellular guardian, creating a 360-degree defense system for the modern, screen-exposed consumer.
The “Cellular-Longevity” Night Repair: Pair with Peptides and Retinoids. EGT’s unique ability to stabilize DNA in the nucleus creates the perfect environment for Retinoids to drive turnover without inciting oxidative stress, while Peptides solidify the dermal matrix.
The “High-Tolerance” Brightening Concentrate: Integrate into Niacinamide-rich emulsions. While EGT prevents the oxidative damage that triggers new pigmentation, Niacinamide improves barrier cohesion and inhibits existing pigment transfer, creating a gentle yet effective brightening strategy for reactive skin.
Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:
ISO 9001
ISO 22000
COSMOS
HALAL
IQNET
Our comprehensive technical dossier—including TDS, MSDS, and COA—is available to support your regulatory and safety assessment requirements.
True innovation in the anti-aging category requires the integration of high-potency, standardized bioactives that operate at the deepest biological level. Stop settling for legacy antioxidants that do not provide genuine, intracellular protection. Integrate the clinical-grade reliability of our high-purity Ergothioneine into your next-generation longevity line.
Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of technical validation reports and stability testing data.
Request your technical dossier and premium-grade, high-purity samples today to initiate the next generation of high-potency, intracellular skin protection.
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