Stearyl Glycyrrhetinate

The Highly Permeable Ester for Advanced Anti-Allergy and Soothing

An ester derived from Glycyrrhetinic Acid, SG is a multifunctional ingredient with strong transdermal absorption. It is primarily known for its potent anti-allergic, soothing, and anti-inflammatory effects, making it an ideal choice for sensitive, troubled, and compromised skin formulations.

CAS No.

13832-70-7

Source

Glycyrrhetinic Acid Derivative

Appearance Color

White Powder

Key Efficacy

Anti-Allergy, Soothing, Moisturizing, Antibacterial

Purity

98%

Solubility

Alcohol Soluble / Water Soluble

The Lipid-Soluble Barrier Architect: 98% Stearyl Glycyrrhetinate for Advanced Sensitive Skin Repair

For prestige skincare brands and high-performance contract manufacturers, traditional soothing ingredients often face a critical bottleneck: poor solubility in oil-based formulas, leading to crystallization, inconsistent textures, and limited dermal penetration. Our 98% High-Purity Stearyl Glycyrrhetinate (SG) is the definitive solution to these formulation constraints. By leveraging an esterified structure, we offer a highly stable, lipid-soluble bioactive that provides profound anti-inflammatory action, enabling you to build premium, irritation-free anhydrous products, sunscreens, and luxury emulsions that deliver immediate, clinical-grade relief.

Unrivaled Efficacy: Clinical & Laboratory Proof

  • Cytokine Neutralization: Clinically validated to suppress the expression of primary pro-inflammatory factors, including IL-1A, TNF-A, and PGE-2, effectively lowering the skin’s inflammatory threshold.

  • Tissue Morphology Restoration: Advanced 3D epidermal skin model (EPIKUTIS) testing demonstrates that concentrations as low as 0.05% – 0.2% significantly improve viable cell morphology and restore stratum corneum thickness in damaged tissue.

  • Enhanced Bioavailability: The esterified molecular structure provides superior transdermal absorption compared to water-soluble precursors, ensuring the active reaches deeper skin layers for sustained barrier recovery.

Core Specifications & Technical Parameters

ParameterGrade (Alcohol Soluble)Grade (Water Soluble)
Active Content (Purity)98%98%
AppearanceWhite PowderWhite Powder
SolubilityAlcohol SolubleWater Soluble
Recommended Use Rate0.1% – 2.0%0.1% – 2.0%
Shelf Life24 Months24 Months
StorageCool, dark, dry, sealed spaceCool, dark, dry, sealed space

Formulation Intelligence: The “Golden Synergy” Blends

Accelerate your R&D pipeline with these strategically optimized pairings designed to deliver market-leading barrier repair:

  • The “Total Barrier Repair” System: Combine with Ceramides (NP/AP/EOP). While Stearyl Glycyrrhetinate neutralizes the “silent inflammation” of reactive skin, the ceramides provide the lipid structural support needed to rebuild the damaged stratum corneum.

  • The “Intensive Calm” Serum: Pair with Hyaluronic Acid. This dual-action approach combines deep-tissue soothing with intensive hydration, creating the perfect therapeutic serum for post-procedural recovery or acute sensitivity.

  • The “Soothing Shield” Sunscreen: Integrate into high-SPF formulations. Stearyl Glycyrrhetinate acts as a functional stabilizer that mitigates the irritation caused by UV-filters while providing a secondary layer of antioxidant and anti-inflammatory defense.

Quality Assurance & Regulatory Excellence

Our production standards reflect the precision required by global dermatological brands, ensuring total supply chain confidence:

  • ISO 9001

  • ISO 22000

  • COSMOS

  • HALAL

  • IQNET

Our comprehensive technical dossier—including TDS, MSDS, and COA—is available to support your regulatory and safety assessment requirements.

Secure Your Competitive Edge in Sensitive Skin Care

Excellence in sensitive skin care is defined by both the potency of the active and the elegance of the delivery system. Stop settling for water-bound alternatives and integrate the high-penetration, lipid-soluble precision of our 98% Stearyl Glycyrrhetinate into your next formulation launch.

Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of 3D skin model efficacy reports and stability documentation.

Request your technical dossier and premium-grade samples today to initiate the next generation of high-potency soothing care.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. is a specialized manufacturer of advanced Functional Skincare Ingredients, providing scalable wholesale solutions for global beauty brands. We offer high-purity bulk supplies of Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. With tailored concentrations (1%–99%) and comprehensive OEM capabilities, our ISO 9001/22000 and COSMOS certified facilities guarantee premium cosmetic-grade quality for every wholesale order.

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