ガンマポリグルタミン酸

γ-ポリグルタミン酸は、 Bacillus subtilisによる発酵によって生産される、天然のアニオン性バイオポリマーです。ヒアルロン酸よりもはるかに多くの水を結合する能力を持つ、スーパー保湿剤として称賛されています。γ-ポリグルタミン酸は、集中的で深い水分補給を提供するだけでなく、皮膚の弾力性をユニークに向上させ、ヒアルロン酸の分解を引き起こす酵素を阻害し、皮膚の天然保湿因子(NMF)組成全体を改善します。

INCI名

ポリグルタミン酸

CAS番号

25513-46-6

出典

バイオテクノロジー発酵

外観

白色~微黄色の粉末または粘性溶液

主な機能

スーパー保湿、弾力性向上、HA分解阻害、NMFブースト、バリアサポート

The New Standard in Moisture: Gamma-Polyglutamic Acid (γ-PGA) for Superior Bio-Hydration

For high-end beauty brands, the limitations of traditional humectants are clear: surface-level hydration is insufficient, and moisture evaporation remains a constant threat to formulation efficacy. As consumer demand shifts toward clinical-grade, biotechnologically advanced ingredients, Gamma-Polyglutamic Acid (γ-PGA) has emerged as the definitive successor to standard Hyaluronic Acid. By combining a massive water-binding capacity with the rare ability to preserve the skin’s endogenous moisture, this natural fermentation-derived active empowers formulators to create the next generation of plumping, barrier-reinforcing, and age-defying skincare.

Unrivaled Efficacy: Clinical & Laboratory Proof

  • 5,000x Water Binding: Possesses an extraordinary capacity to bind up to 5,000 times its weight in water, creating a powerful, long-lasting moisture reservoir that outperforms standard Hyaluronic Acid in comparative clinical studies.

  • ヒアルロニダーゼ阻害: Acts as a potent inhibitor of Hyaluronidase, the enzyme responsible for the degradation of endogenous Hyaluronic Acid, effectively protecting the skin’s native moisture-retention pathways.

  • Biotech-Driven NMF Synthesis: Actively stimulates the production of Natural Moisturizing Factors (NMFs) such as UCA and Lactic Acid, providing a sustainable, deep-tissue hydration boost.

  • Immediate Plumping Effect: Creates a breathable, non-tacky film that minimizes Transepidermal Water Loss (TEWL) while providing a rapid smoothing and firming effect on the skin’s surface.

Core Specifications & Technical Parameters

パラメータ仕様
分子量>100 kDa (High MW for film-forming)
10. ≥ 40%Standardized concentration (Aqueous solution/Powder)
外観Clear to slightly opalescent liquid / White powder
溶解性高い水溶性
pH安定範囲4.0 – 7.0
推奨使用量0.05% – 0.5% (as high-purity powder)
賞味期限24ヶ月
保管方法Store in a cool, dark, sealed container

Formulation Intelligence: The “Golden Synergy” Blends

Accelerate your R&D pipeline with these strategically optimized pairings:

  • The “Total Moisture” Matrix: Combine with Glycerin and low-molecular weight Hyaluronic Acid. While the Glycerin draws immediate water into the stratum corneum, the γ-PGA “locks” it in and prevents degradation, providing a multi-layer, 24-hour hydration architecture.

  • The “Luminous Barrier” Complex: Pair with ナイアシンアミド. This synergy repairs the skin barrier while providing an immediate smoothing effect, perfect for high-performance serums that target both texture and dullness.

  • The “Structural Age-Defiance” Serum: Integrate with Vitamin C Derivatives. The γ-PGA provides the stable hydration necessary to mitigate the potential irritation of active Vitamin C while the plumping effect of the PGA maximizes the anti-aging visual results.

Quality Assurance & Regulatory Excellence

Our production facility operates at the intersection of biotechnology and compliance, providing the documentation required for the most stringent global markets:

  • ISO 9001

  • ISO 22000

  • COSMOS

  • HALAL

  • IQNET

Our comprehensive technical dossier—including TDS, MSDS, COA, and clinical comparative hydration studies—is available to support your regulatory and safety assessment teams.

Secure Your Competitive Edge in Moisture Tech

Standard hydration is a commodity; clinical-grade moisture is a competitive advantage. Move your formulations beyond the limitations of legacy humectants and integrate the superior performance of Gamma-Polyglutamic Acid.

Contact our technical advisory team to secure your professional evaluation samples and gain immediate, priority access to our full library of technical validation reports and stability studies.

Request your technical dossier and premium-grade samples today to initiate the next generation of high-potency, super-hydrating skincare.

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